ABSTRACT
Calmodulin(CaM),as major intracellular Ca 2+ signal transductor,is a ubiquitous, multifunctional protein in eukaryotic cells,invovled in a wide variety of cellular processes . Study of the structure and molecular recognition mechanism of CaM helps better understanding intracellular Ca 2+ signaling system and molecular recognition of protein-protein interaction,giving new insight into medicine development and clinical therapy. This paper reviews progress in the studies of molecular recognition of calmodulin in recent past years.
ABSTRACT
Objective To describe and study the abdominal computed tomographic(CT)findings in patients with pulmonary lymphangiomyomatosis(PLAM). Methods Abdominal CT was performed in all the seven cases with histopathologically proved pulmonary lymphangiomyomatosis, then the abdominal CT findings were described. Results Six of these 7 cases had positive abdominal CT findings:renal angiomyolipoma in 2 cases,one of these patients also had dilatation of the thoracic duct and pleural effusion;enlarged abdominal lymph nodes in 2 cases, one patient also had ascites and pleural effusion.Others findings included lymphangiomyoma and uterine tumor in one, hepatic angiomyolipoma in one. Conclusion PLAM can be complicated by abdominal multiorganic pathology frequently,abdominal examination in patients with PLAM must be valued greatly,CT examination is of important significance to discover and diagnosis abdominal pathology.
