Subject(s)
Hernia/diagnosis , Orbit/injuries , Orbital Fractures/diagnosis , Wounds, Nonpenetrating/diagnosis , Adolescent , Diagnosis, Differential , Hernia/etiology , Humans , Magnetic Resonance Imaging , Male , Orbital Fractures/etiology , Tomography, X-Ray Computed , Wounds, Nonpenetrating/etiologySubject(s)
Acetazolamide/adverse effects , Calcinosis/chemically induced , Corneal Diseases/chemically induced , Corneal Stroma , Dexamethasone/adverse effects , Timolol/adverse effects , Aged , Female , Humans , Keratitis, Dendritic/drug therapy , Keratitis, Dendritic/surgery , Keratoplasty, Penetrating , Male , Recurrence , Uveitis/surgeryABSTRACT
Clinical observation of eight patients with superficial stromal precipitation of calcium phosphate is presented. In all cases the predisposing factors for the formation of these depositions were: epithelial defects and the combined use of topical dexamethasone phosphate or prednisolone phosphate with topical beta-blocking agents. In two patients the medication that gave rise to these precipitates was used without preservatives, suggesting that the medication itself and not the preservatives contribute to the deposits. Discontinuance of simultaneous administration of the steroids and beta-blocking agents prevented further formation of precipitates. The authors suggest an interaction between simultaneously given steroid and beta-blocking agents, giving rise to calcium phosphate precipitates when an epithelial defect is present which allows easy access to the superficial corneal stroma.
Subject(s)
Calcinosis/chemically induced , Corneal Diseases/chemically induced , Corneal Stroma , Aged , Aged, 80 and over , Calcium Phosphates/analysis , Cataract Extraction , Corneal Stroma/chemistry , Dexamethasone/adverse effects , Electron Probe Microanalysis , Female , Humans , Intraocular Pressure , Keratoplasty, Penetrating , Lenses, Intraocular , Male , Middle Aged , Prednisolone/adverse effects , Timolol/adverse effectsABSTRACT
Ninety patients were studied who had been admitted to Dijkzigt Hospital in Rotterdam between January 1980 and April 1987 with subarachnoid haemorrhage (SAH) due to an aneurysm at or near the junction of the internal carotid artery with the posterior communicating artery (IC-PC). An evaluation was made of the early neuro-opthalmological symptoms and the mortality in patients with paresis of the oculomotor nerve (N.III). The importance of early recognition of the condition is emphasized and a prospective investigation of the early symptoms of SAH in ophthalmological practices in the Netherlands is proposed.
