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Pediatr Infect Dis J ; 30(12): 1107-9, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21796013

ABSTRACT

We studied the potential benefits of introducing a rapid enterovirus molecular test in children with enterovirus meningitis. The 2 groups of pediatric patients were comparable with respect to clinical and laboratory data, but differed in availability of enterovirus test results. In the control group, the results were available within 3 to 7 days, whereas in the study group, rapid enterovirus molecular test results were available within 3 to 24 hours. The median duration of hospitalization and the duration of antibiotics were significantly reduced to, respectively, 2 days and 1 day in the study group when compared with the control group (P < 0.001). Mean costs per patient calculation showed an average reduction of more than US $1450 (P < 0.001).


Subject(s)
Anti-Bacterial Agents/therapeutic use , Enterovirus/isolation & purification , Meningitis, Aseptic/cerebrospinal fluid , Meningitis, Aseptic/virology , Cerebrospinal Fluid/virology , Child , Enterovirus/genetics , Humans , Length of Stay/statistics & numerical data , Meningitis, Aseptic/drug therapy , Molecular Diagnostic Techniques , Prospective Studies , Real-Time Polymerase Chain Reaction , Statistics, Nonparametric , Virology
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