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Reduction of liver glutathione peroxidase activity and deficiency of serum selenium in patients with hepatocellular carcinoma.

Corrocher, R; Casaril, M; Bellisola, G; Gabrielli, G; Hulpe, M; Garofoli, E; Nicoli, N.

Tumori ; 72(6): 617-9, 1986 Dec 31.

Article in English | MEDLINE | ID: mdl-3027933

ABSTRACT

Twelve adults with hepatocellular carcinoma (HCC) and 8 individuals with histologically normal liver, were measured for serum selenium concentration and glutathione peroxidase (GSH-Px) of liver tissue. It was found a reduced serum selenium and liver GSH-Px in patients with HCC. Serum selenium concentration and the enzyme activity were positively correlated (p less than 0.01). The increased risk of carcinoma in selenium deficiency may be partially due to a reduced activity of GSH-Px, one of the most important scavenger enzymes of oxygen toxic radicals.

Subject(s)

Carcinoma, Hepatocellular/metabolism , Glutathione Peroxidase/analysis , Liver Neoplasms/metabolism , Liver/enzymology , Selenium/blood , Female , Humans , Male

[Protoporphyrins and anemia in hemodialysed patients. Correlations with cutaneous changes]. / Protoporfirine e anemia in pazienti emodializzati. Correlazioni con alterazioni cutanee.

Barba, A; Spagnolli, A; Ferrari, S; Hulpe, M; Gulino, S.

G Ital Dermatol Venereol ; 120(2): 109-11, 1985.

Article in Italian | MEDLINE | ID: mdl-4007949

Subject(s)

Kidney Failure, Chronic/blood , Porphyrins/blood , Protoporphyrins/blood , Renal Dialysis/adverse effects , Anemia/blood , Female , Ferritins/metabolism , Humans , Male , Porphyrias/pathology , Skin Diseases/pathology

[Determination of zinc protoporphyrins in pregnancy and the puerperium]. / Il dosaggio delle zincoprotoporfirine in gravidanza ed in puerperio.

Ferrari, S; Pezzini, M B; Hulpe, M; Bonadonna, G; Borruto, F.

Minerva Ginecol ; 33(4): 313-4, 1981 Apr.

Article in Italian | MEDLINE | ID: mdl-7243072

Subject(s)

Porphyrins/blood , Postpartum Period , Pregnancy , Protoporphyrins/blood , Adult , Female , Humans

[Considerations on iron metabolism in pregnancy]. / Alcune considerazioni sul metabolismo del ferro in gravidanza.

Ferrari, S; Hulpe, M; Pezzini, M B; Zanoio, L.

Minerva Ginecol ; 32(1-2): 15-20, 1980.

Article in Italian | MEDLINE | ID: mdl-7366884

Subject(s)

Anemia, Hypochromic , Anemia/etiology , Iron/metabolism , Pregnancy Complications, Hematologic , Adult , Female , Humans , Pregnancy

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