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1.
BMC Health Serv Res ; 23(1): 1204, 2023 Nov 04.
Article in English | MEDLINE | ID: mdl-37924092

ABSTRACT

INTRODUCTION: A shortage of doctors is currently one of the biggest challenges faced by the healthcare workforce in the United Kingdom (UK). While plans are in place to increase the number of medical school places, in the short-term this gap will need to continue to be filled by the international recruitment of doctors. The aim of this study is to identify key factors that explain the patterns of migration of doctors to the UK, in order to aid the development of policies to recruit and retain a sustainable workforce. METHODS: We analysed General Medical Council (GMC) secondary data on the patterns of migration of internationally trained doctors (2009-2019). Qualitative interviews were conducted with 17 stakeholders by videoconferencing which were audio-recorded, transcribed and thematically analysed using NVivo. RESULTS: In 2019, 34.5% of UK doctors were trained internationally mainly in India, Pakistan, Italy, Nigeria, Greece, Romania and Egypt. Most new registrations by internationally trained doctors from 2009-2019 did not have a specialty at the time of initial registration (96.2% in 2019). Only a relatively small number of these doctors go on to gain specialist or GP registration (11.6% within 5 years and 27.2% within 10 years of registration). The stakeholder interviews highlighted training opportunities and career progression as the main drivers of migration. The barriers internationally trained doctors face regarding specialty training included differences between UK and destination health systems, systematic bias, bureaucracy and selection processes not being accessible. CONCLUSION: This study makes a contribution to the literature by identifying recent patterns in the migration of doctors to the UK. The UK's dependence on internationally trained doctors has important global implications as source countries are losing skilled health workers which is undermining their health systems. In keeping with the WHO Global Code on the International Recruitment of Healthcare Personnel, policymakers need to consider how to reduce the UK's reliance on internationally trained doctors, particularly from countries on the safeguard list whilst continuing the drive to increase medical school places. Additional support is required for internationally trained doctors, to ensure that they get on the training programmes they seek, enabling their career progression.


Subject(s)
Physicians , Humans , United Kingdom , Health Personnel , Workforce , Romania , Career Choice
2.
Hum Resour Health ; 21(1): 11, 2023 02 14.
Article in English | MEDLINE | ID: mdl-36788569

ABSTRACT

BACKGROUND: Many high-income countries are heavily dependent on internationally trained doctors to staff their healthcare workforce. Over one-third of doctors practising in the UK received their primary medical qualification abroad. Simultaneously, an average of around 2.1% of doctors leave the UK medical workforce annually to go overseas. The aim of this study was to identify the drivers and barriers of international migration of doctors to and from the UK. METHODS: A scoping review was conducted. We searched EMBASE, MEDLINE, CINAHL, ERIC and BEI in January 2020 (updated October 2021). Grey literature and citation searching were also carried out. Empirical studies reporting on the drivers and barriers to the international migration of doctors to and from the UK published in the English language from 2009 to present were included. The drivers and barriers were coded in NVivo 12 building on an existing framework. RESULTS: 40 studies were included. 62% were quantitative, 18% were qualitative, 15% were mixed-methods and 5% were literature reviews. Migration into and out of the UK is determined by a variety of macro- (global and national factors), meso- (profession led factors) and micro-level (personal factors). Interestingly, many of the key drivers of migration to the UK were also factors driving migration from the UK, including: poor working conditions, employment opportunities, better training and development opportunities, better quality of life, desire for a life change and financial reasons. The barriers included stricter immigration policies, the registration process and short-term job contracts. CONCLUSIONS: Our research contributes to the literature by providing a comprehensive up-to-date review of the drivers and barriers of migration to and from the UK. The decision for a doctor to migrate is multi-layered and is a complex balance between push/pull at macro-/meso-/micro-levels. To sustain the UK's supply of overseas doctors, it is vital that migration policies take account of the drivers of migration particularly working conditions and active recruitment while addressing any potential barriers. Immigration policies to address the impact of Brexit and the COVID-19 pandemic on the migration of doctors to and from the UK will be particularly important in the immediate future. Trial registration PROSPERO CRD42020165748.


Subject(s)
COVID-19 , Emigration and Immigration , Humans , United Kingdom , European Union , Pandemics , Quality of Life
3.
Ir J Psychol Med ; 39(2): 173-184, 2022 06.
Article in English | MEDLINE | ID: mdl-32458773

ABSTRACT

OBJECTIVES: Often referred to as psychotic experiences, unusual perceptual experiences, thoughts and beliefs (UPTBs) are not uncommon in youth populations. Phenomenological studies of these experiences are lacking. This study aimed to (1) describe the phenomenological characteristics of UPTBs in a sample of young adolescents and (2) explore how young people made sense of those experiences. METHODS: Participants were 53 young people aged 11-13 years from a population-based study of mental health. All met criteria for UPTBs following clinical interviews as part of the study. Documentary data on UPTBs in the form of transcribed notes, recorded during clinical interviews, were analysed using content analysis. Data on UPTBs were coded, organised into categorical themes and quantified using descriptive statistics. Qualitative themes on how participants made sense of their experiences were identified. RESULTS: Participants reported UPTBs across four domains: auditory verbal, auditory non-verbal, non-auditory perceptual experiences and unusual thoughts and beliefs. UPTBs were phenomenologically rich and diverse. Young people sought to make sense of their experiences in multiple ways: normalising them, externalising them by attributing them to paranormal entities and distancing them from psychiatric explanations. Uncertainty about the source of UPTBs was identified as a superordinate theme. CONCLUSION: Findings from this study offer new insights into the phenomenological qualities and characteristics of UPTBs in young adolescents. They also reveal that early adolescents may not make sense of their experiences within a psychiatric framework. These findings highlight the need to develop a more phenomenologically sensitive and nuanced approach to studying UPTBs in young people.


Subject(s)
Mental Disorders , Adolescent , Humans , Mental Health
4.
Ir J Psychol Med ; 39(2): 207-222, 2022 06.
Article in English | MEDLINE | ID: mdl-33969817

ABSTRACT

OBJECTIVES: Hallucinations and delusions that occur in the absence of a psychotic disorder are common in children and adolescents. Longitudinal phenomenological studies exploring these experiences are notably lacking. The objective of the current paper was to explore the phenomenology and characteristics of hallucinations and delusions from early adolescence to early adulthood. METHODS: Participants were 17 young people aged 18-21 years from the general population, all of whom had a history of childhood hallucinations and/or delusions. Longitudinal data on the phenomenological characteristics and attributions of reported hallucinatory and delusional phenomena spanning nine years were explored using content analysis. RESULTS: Hallucinatory and delusional phenomena were transient for two-thirds of the sample. The remaining one-third reported reoccurring hallucinatory and delusional phenomena into early adulthood. In those, two typologies were identified: (1) Paranormal typology and (2) Pathological typology. The former was characterised by hallucinatory and delusional phenomena that were exclusively grounded in subcultural paranormal or spiritual belief systems and not a source of distress. The latter was characterised by delusion-like beliefs that were enmeshed with individuals' mood states and a source of distress. The perceived source, the subcultural context and how young people appraised and integrated their experiences differentiated the Paranormal and Pathological typologies. CONCLUSIONS: Not all hallucinatory and delusion-like experiences are psychotic-like in nature. To reliably differentiate between pathological and non-pathological hallucinations and delusions, assessments need to explore factors including the phenomenology of individuals' experiences, how people make sense and appraise them, and the subcultural contexts within which they are experienced.


Subject(s)
Delusions , Psychotic Disorders , Adolescent , Adult , Child , Delusions/epidemiology , Hallucinations/epidemiology , Humans , Longitudinal Studies , Psychotic Disorders/epidemiology
5.
Hum Resour Health ; 17(1): 97, 2019 12 09.
Article in English | MEDLINE | ID: mdl-31815621

ABSTRACT

BACKGROUND: Medicine is a high-status, high-skill occupation which has traditionally provided access to good quality jobs and relatively high salaries. In Ireland, historic underfunding combined with austerity-related cutbacks has negatively impacted job quality to the extent that hospital medical jobs have begun to resemble extreme jobs. Extreme jobs combine components of a good quality job-high pay, high job control, challenging demands, with those of a low-quality job-long working hours, heavy workloads. Deteriorating job quality and the normalisation of extreme working is driving doctor emigration from Ireland and deterring return. METHODS: Semi-structured qualitative interviews were conducted with 40 Irish emigrant doctors in Australia who had emigrated from Ireland since 2008. Interviews were held in July-August 2018. RESULTS: Respondents reflected on their experiences of working in the Irish health system, describing hospital workplaces that were understaffed, overstretched and within which extreme working had become normalised, particularly in relation to long working hours, fast working pace, doing more with less and fighting a climate of negativity. Drawing on Hirschman's work on exit, voice and loyalty (1970), the authors consider doctor emigration as exit and present respondent experiences of voice prior to emigration. Only 14/40 respondent emigrant doctors intend to return to work in Ireland. DISCUSSION: The deterioration in medical job quality and the normalisation of extreme working is a key driver of doctor emigration from Ireland, and deterring return. Irish trained hospital doctors emigrate to access good quality jobs in Australia and are increasingly likely to remain abroad once they have secured them. To improve doctor retention, health systems and employers must mitigate a gainst the emergence of extreme work in healthcare. Employee voice (about working conditions, about patient safety, etc.) should be encouraged and used to inform health system improvement and to mitigate exit.


Subject(s)
Attitude of Health Personnel , Emigrants and Immigrants/psychology , Foreign Medical Graduates/psychology , Foreign Medical Graduates/statistics & numerical data , Job Satisfaction , Professional Practice Location/statistics & numerical data , Adult , Australia , Emigrants and Immigrants/statistics & numerical data , Emigration and Immigration/statistics & numerical data , Female , Humans , Interviews as Topic , Ireland/ethnology , Male , Physicians/psychology , Physicians/statistics & numerical data , Workload/psychology , Workload/statistics & numerical data , Young Adult
6.
J Fish Biol ; 92(3): 727-751, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29537089

ABSTRACT

Wild fish populations are currently experiencing unprecedented pressures, which are projected to intensify in the coming decades. Developing a thorough understanding of the influences of both biotic and abiotic factors on fish populations is a salient issue in contemporary fish conservation and management. During the 50th Anniversary Symposium of The Fisheries Society of the British Isles at the University of Exeter, UK, in July 2017, scientists from diverse research backgrounds gathered to discuss key topics under the broad umbrella of 'Understanding Fish Populations'. Below, the output of one such discussion group is detailed, focusing on tools used to investigate natural fish populations. Five main groups of approaches were identified: tagging and telemetry; molecular tools; survey tools; statistical and modelling tools; tissue analyses. The appraisal covered current challenges and potential solutions for each of these topics. In addition, three key themes were identified as applicable across all tool-based applications. These included data management, public engagement, and fisheries policy and governance. The continued innovation of tools and capacity to integrate interdisciplinary approaches into the future assessment and management of fish populations is highlighted as an important focus for the next 50 years of fisheries research.


Subject(s)
Fisheries , Fishes/physiology , Animals , Congresses as Topic , Conservation of Natural Resources/methods , Interdisciplinary Communication , Models, Biological , Policy , Population Dynamics , Telemetry
7.
Proc Natl Acad Sci U S A ; 115(12): 3072-3077, 2018 03 20.
Article in English | MEDLINE | ID: mdl-29483242

ABSTRACT

The extent of increasing anthropogenic impacts on large marine vertebrates partly depends on the animals' movement patterns. Effective conservation requires identification of the key drivers of movement including intrinsic properties and extrinsic constraints associated with the dynamic nature of the environments the animals inhabit. However, the relative importance of intrinsic versus extrinsic factors remains elusive. We analyze a global dataset of ∼2.8 million locations from >2,600 tracked individuals across 50 marine vertebrates evolutionarily separated by millions of years and using different locomotion modes (fly, swim, walk/paddle). Strikingly, movement patterns show a remarkable convergence, being strongly conserved across species and independent of body length and mass, despite these traits ranging over 10 orders of magnitude among the species studied. This represents a fundamental difference between marine and terrestrial vertebrates not previously identified, likely linked to the reduced costs of locomotion in water. Movement patterns were primarily explained by the interaction between species-specific traits and the habitat(s) they move through, resulting in complex movement patterns when moving close to coasts compared with more predictable patterns when moving in open oceans. This distinct difference may be associated with greater complexity within coastal microhabitats, highlighting a critical role of preferred habitat in shaping marine vertebrate global movements. Efforts to develop understanding of the characteristics of vertebrate movement should consider the habitat(s) through which they move to identify how movement patterns will alter with forecasted severe ocean changes, such as reduced Arctic sea ice cover, sea level rise, and declining oxygen content.


Subject(s)
Animal Migration , Databases, Factual , Oceans and Seas , Vertebrates , Animals , Ecosystem
9.
J Fish Biol ; 87(6): 1313-21, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26511427

ABSTRACT

A large, pregnant, female bull shark Carcharhinus leucas was tracked migrating from Seychelles across open ocean to south-east Madagascar, c. 2000 km away, and back again. In Madagascar, the shark spent a prolonged period shallower than 5 m, consistent with entering estuarine habitat to pup, and upon return to Seychelles the shark was slender and no longer gravid. This represents an unprecedented return migration across the open ocean for a C. leucas and highlights the need for international collaboration to manage the regional C. leucas population sustainably.


Subject(s)
Animal Migration , Sharks/physiology , Animals , Ecosystem , Female , Madagascar , Oceans and Seas
10.
Australas Radiol ; 49(2): 104-7, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15845044

ABSTRACT

Computed tomography pelvimetry is still used in clinical practice. We wished to quantify observer error in order to assess the level of confidence with which pelvic measurements can be described as adequate or inadequate. Anteroposterior inlet, anteroposterior outlet, transverse inlet and interspinous distances were measured from 11 CT pelvimetry examinations by five observers at one institution. Three CT pelvimetries were measured by five observers at a second institution. Intraobserver and interobserver variation was assessed using analysis of variance. Reliability of measurements was assessed using intraclass correlation coefficient. Combined error was calculated to determine 95% confidence limits for published minimum recommended pelvic measurements. The standard error of measurement, combining all sources, for measurement of the bony dimensions of the pelvis were: for anteroposterior inlet, 2.0 mm; anteroposterior outlet, 6.9 mm; transverse inlet, 1.3 mm; and interspinous distance, 2.1 mm. The 95% confidence interval around the recommended anteroposterior outlet of 100 mm was 88.5-111.3 mm. Observer variation in measurement of anteroposterior outlet is so large as to make the measurement of doubtful clinical utility.


Subject(s)
Diagnostic Errors , Pelvimetry/methods , Tomography, X-Ray Computed , Analysis of Variance , Confidence Intervals , Female , Humans , Observer Variation , Predictive Value of Tests , Pregnancy , Reproducibility of Results
11.
Ultrasound Med Biol ; 30(2): 271-6, 2004 Feb.
Article in English | MEDLINE | ID: mdl-14998679

ABSTRACT

Dual-beam vector Doppler has the potential to improve peak systolic blood velocity measurement accuracy by automatically correcting for the beam-flow Doppler angle. Using a modified linear-array system with a split receive aperture, we have assessed the angle-dependence over Doppler angles of 40 degrees -70 degrees and the reproducibility of the dual-beam blood maximum velocity estimate measured in the common carotid arteries (CCA) 1 to 2 cm prior to the bifurcation of 9 presumed-healthy volunteers. The velocity magnitude estimate was reduced by approximately 7.9% as the angle between the transmit beam and the vessel axis was increased from 40 degrees to 70 degrees. With repeat measurements made, on average, approximately 6 weeks apart, the 95% velocity magnitude limits of agreement were as follows: Intraobserver -41.3 to +45.2 cm/s; interobserver -29.6 to +46.8 cm/s. There was an 8.6 cm/s interobserver bias in velocity magnitude. We conclude that the dual-beam vector Doppler system can measure blood velocity within its scan plane with low dependence on angle and with similar reproducibility to that of single-beam systems.


Subject(s)
Carotid Artery, Common/diagnostic imaging , Ultrasonography, Doppler/methods , Adult , Blood Flow Velocity/physiology , Carotid Artery, Common/physiology , Female , Humans , Male , Middle Aged , Reproducibility of Results
12.
Adm Radiol J ; 20(1): 7-11, 2001.
Article in English | MEDLINE | ID: mdl-11263112

ABSTRACT

The aim of this investigation was to examine the impact of a six-month high intensity strength-training program on lumbar bone mineral density (BMD), trunk and lower limb strength in a population of Australian women aged 50 years and over. A subject pool of 44 women were recruited and randomly allocated into either strength training (n = 19) or active control (n = 25) groups. All subjects trained twice weekly in either a 50 minute supervised strength training session that progressed from 60% one repetition maximum (1RM) to 90% 1RM or a 50 minute group walk session. Measurements included a lumbar (L2-L4) BMD scan: peak isokinetic trunk strength and a dynamic 1RM squat as a measure of lower body strength. No significant group differences in lumbar BMD were evident at the completion of training. However, a significant (p < 0.05) within group change was apparent for the active control group as lumbar BMD decreased 1.7% below baseline testing. A significant (p < 0.05) group difference was evident with the strength trained group increasing peak isokinetic trunk strength (19.3%) and 1RM squat strength (34.4%) above that of the active controls. It was concluded that strength training provides an effective means for increasing trunk and lower limb strength in women over 50 years. The impact of strength training on lumbar BMD was not conclusive in the present study.


Subject(s)
Bone Density/physiology , Exercise Therapy/methods , Leg/physiology , Lumbar Vertebrae/physiology , Muscle, Skeletal/physiology , Absorptiometry, Photon , Aged , Australia , Female , Humans , Lumbar Vertebrae/diagnostic imaging , Middle Aged , Physical Fitness/physiology , Treatment Outcome
13.
Med Sci Sports Exerc ; 32(6): 1043-50, 2000 Jun.
Article in English | MEDLINE | ID: mdl-10862528

ABSTRACT

PURPOSE: This study examined the effects of 24 wk of high intensity strength training or low intensity walking on lumbar bone mineral density (BMD), muscular strength, and calcium turnover in Australian women either taking hormone replacement therapy (HRT) or not taking HRT. METHODS: A subject pool of 64 women between 45-65 yr and randomly allocated into weights (N = 21), walking (N = 20), weightsHRT (N = 14), and walkingHRT (N = 9) groups completed this study. All subjects trained twice weekly in either a 50-min walking or weight-training program (60-90% IRM). Measurements included maximal isometric knee strength, IRM bench press, IRM squat, isokinetic back strength, lumbar (L2-L4) BMD, serum osteocalcin, and urinary deoxypyridinoline crosslinks (Dpd). RESULTS: No significant group differences in BMD were evident at the completion of training. However, a significant (P < 0.05) within group change was apparent for the walking group since BMD decreased 1.3% below baseline testing. Osteocalcin levels increased significantly (P < 0.05) in the walking (22%) group. Maximal bench press and squat strength improved significantly (P < 0.05) in the weights (25.8% and 37.7%) and weightsHRT (25.4% and 35.7%) groups. The weights group also increased significantly (P < 0.05) in isokinetic back strength (22.2%). CONCLUSION: It was concluded that short-term high intensity resistance training provides an effective means for increasing muscular strength in women between 45 and 65 yr. The training effects on lumbar BMD were not apparent in the present study.


Subject(s)
Bone Density , Calcium/metabolism , Exercise , Physical Fitness , Aged , Female , Humans , Lumbar Vertebrae , Middle Aged , Muscle, Skeletal/physiology , Weight-Bearing
14.
J Gen Intern Med ; 14(5): 281-6, 1999 May.
Article in English | MEDLINE | ID: mdl-10337037

ABSTRACT

OBJECTIVE: To determine the relative importance of medical and nonmedical factors influencing generalists' decisions to refer, and of the factors that might avert unnecessary referrals. DESIGN: Prospective survey of all referrals from generalists to subspecialists over a 5-month period. SETTING: University hospital outpatient clinics. PARTICIPANTS: Fifty-seven staff physicians in general internal medicine, family medicine, dermatology, orthopedics, gastroenterology, and rheumatology. MEASUREMENTS AND MAIN RESULTS: For each referral, the generalist rated a number of medical and nonmedical reasons for referral, as well as factors that may have helped avert the referral; the specialist seeing the patient then rated the appropriateness, timeliness, and complexity of the referral. Both physicians rated the potential avoidability of the referral by telephone consultation. Generalists were influenced by a combination of both medical and nonmedical reasons for 76% of the referrals, by only medical reasons in 20%, and by only nonmedical reasons in 3%. In 33% of all referrals, generalists felt that training in simple procedures or communication with a generalist or specialist colleague would have allowed them to avoid referral. Specialists felt that the vast majority of referrals were timely (as opposed to premature or delayed) and of average complexity. Although specialists rated most referrals as appropriate, 30% were rated as possibly appropriate or inappropriate. Generalists and specialists failed to agree on the avoidability of 34% of referrals. CONCLUSIONS: Generalists made most referrals for a combination of medical and nonmedical reasons, and many referrals were considered avoidable. Increasing procedural training for generalists and enhancing informal channels of communication between generalists and subspecialists might result in more appropriate referrals at lower cost.


Subject(s)
Family Practice/statistics & numerical data , Medicine/methods , Outpatients/statistics & numerical data , Referral and Consultation/statistics & numerical data , Specialization , Ambulatory Care/methods , Data Collection , Decision Making , Family Practice/methods , Female , Humans , Male , Medicine/statistics & numerical data , Prospective Studies , Referral and Consultation/standards , United States
16.
Antimicrob Agents Chemother ; 22(1): 170-1, 1982 Jul.
Article in English | MEDLINE | ID: mdl-7125629

ABSTRACT

The biliary excretion of six cephalosporins was examined in normal and partially hepatectomized rats. Cefamandole, cefazolin, cefuroxime, cefoxitin, and cephradine were excreted well in normal animals. In partially hepatectomized rats, the cumulative percentage of excretion reached only 11 to 36.8% of the control levels. Cephaloridine was excreted poorly in both groups.


Subject(s)
Bile/metabolism , Cephalosporins/metabolism , Animals , Hepatectomy , Liver/metabolism , Male , Protein Binding , Rats , Rats, Inbred Strains
17.
Br J Plast Surg ; 35(2): 150-5, 1982 Apr.
Article in English | MEDLINE | ID: mdl-7082888

ABSTRACT

Xomed microsutures have recently become available in this country. Three different suture types (10/0 taper needle, 10/0 MET needle, and 11/0 taper needle) were tested for their effect on the patency and strength of the anastomosis 0, 1, and 3 weeks post-operatively. Scanning electron micrographs of an anastomosis with each of the two 10/0 sutures and of both 10/0 needles were also studied. Another standard 10/0 suture (Ethicon) was photographed for comparison. Patency was not affected by suture type. The 10/0 MET needle produced the strongest anastomosis at the time intervals studied. Breaking-load values were highest in all needles 1 week post-operatively. Electron micrographs of the two 10/0 needles show that the MET point is very much sharper than the taper needles. Electron micrographs of the anastomosis indicated that the MET needle also causes less damage around the suture.


Subject(s)
Femoral Artery/surgery , Nylons , Animals , Femoral Artery/ultrastructure , Microscopy, Electron, Scanning , Microsurgery/instrumentation , Needles , Rats , Rats, Inbred Strains , Stress, Mechanical , Sutures , Tensile Strength
18.
Br J Plast Surg ; 34(4): 441-5, 1981 Oct.
Article in English | MEDLINE | ID: mdl-7296149

ABSTRACT

An experimental dorsal rat skin flap which produces a consistent pattern of necrosis is described. As judged by the area of necrosis in this flap, short post-operative courses and several vasodilator agents failed to increase flap survival. However it is not possible to conclude from this that those agents did not influence small vessel blood flow. Necrotic flaps in rats may not be the most appropriate models in which to test the effect of vasodilator agents.


Subject(s)
Skin/pathology , Surgical Flaps , Vasodilator Agents/therapeutic use , Animals , Graft Survival/drug effects , Male , Necrosis , Rats , Rats, Inbred Strains
19.
Br J Plast Surg ; 34(4): 446-50, 1981 Oct.
Article in English | MEDLINE | ID: mdl-7028198

ABSTRACT

In a controlled study of the rat abdominal pedicle flap the area of flap necrosis was not reduced by a course of treatment with isoxsuprine. Animals receiving placebo injections of saline showed significantly less flap necrosis than those treated with the drug.


Subject(s)
Isoxsuprine/therapeutic use , Surgical Flaps , Animals , Body Weight , Clinical Trials as Topic , Graft Survival/drug effects , Male , Necrosis , Rats , Rats, Inbred Strains , Skin/pathology
20.
J Nucl Med ; 22(1): 18-21, 1981 Jan.
Article in English | MEDLINE | ID: mdl-7452351

ABSTRACT

An in vivo technique for assessment of the relative contributions of hepatic artery and portal vein to liver perfusion has been developed in the rat. Dynamic scintigrams have been obtained following i.v. bolus injection of Tc-99m sulfur colloid. Temporal separation of the arterial and venous phases has been verified by hepatic-arterial ligation and portacaval diversion. The former procedure abolishes the early arterial phase of normal uptake. Portacaval diversion similarly eliminates the delayed venous phase. Assessment of the individual components of liver perfusion is of promise in the investigation of hepatic dysfunction.


Subject(s)
Hepatic Artery/diagnostic imaging , Liver Circulation , Portal Vein/diagnostic imaging , Technetium , Animals , Colloids , Liver/diagnostic imaging , Liver Diseases/diagnostic imaging , Male , Radionuclide Imaging , Rats , Sulfur , Time Factors
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