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Antimicrob Agents Chemother ; 3(6): 742-3, 1973 Jun.
Article in English | MEDLINE | ID: mdl-4790625

ABSTRACT

BL-20803 induced interferon in mice when administered via oral or parenteral routes. During multiple dosing with the drug at 48-h intervals, animals exhibited a hyporesponsive state to the third treatment. Inhibition of vaccinia virus infection was correlated with interferon induction.


Subject(s)
Interferon Inducers/pharmacology , Quinolines/pharmacology , Animals , Diamines/administration & dosage , Diamines/pharmacology , Dose-Response Relationship, Drug , Female , Interferon Inducers/administration & dosage , Mice , Molecular Weight , Pyrazoles/administration & dosage , Pyrazoles/pharmacology , Quinolines/administration & dosage , Time Factors
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