ABSTRACT
Stereotactic ablative radiotherapy (SABR) has been demonstrated to provide excellent local control in several malignancies. Recent reports have suggested that this ablative dose may impact disease outside of the radiated area. Furthermore, these studies have implicated immune modulation as the primary mechanism of disease response outside the irradiated area. More specifically, T-cell stimulation and tumor necrosis factor-α modulation following high dose irradiation have been suggested as the responsible components of this phenomenon. In addition, the "abscopal effect" may play a role in disease response outside of the radiated area. We review the current literature regarding the effects of ablative radiation therapy, the potential for immune modulation from it, and the mechanisms of the distant effects it elicits.
ABSTRACT
This poster describes research on the workflow of paramedics during disaster response. After thorough solicitation of feedback from the user community, we translated the user workflows into data models that could be encompassed into information technologies for disaster response. Three data models described in this paper are: tasks to be completed by responders, resources used for each task, and communications link between responders. This work has been employed in Advanced Health and Disaster Aid Network (AID-N) architecture.
