1.
Bioorg Med Chem Lett
; 9(14): 1895-900, 1999 Jul 19.
Article
in English
| MEDLINE
| ID: mdl-10450949
ABSTRACT
Rational drug design utilizing a receptor homology model of the human muscarinic M1 receptor led to the discovery of the highly potent (Ki = 2 nM), efficacious, and in vivo functionally-selective M1 agonist, WAY-132983.