ABSTRACT
Complement activity (CA) was studied in 40 patients with acute leukosis, in 75 patients with chronic myeloblastic leukosis and in 28 patients with multiple myeloma. Results indicated that unchanged CA was associated with a usual clinical course of the diseases, its fall resulted in infectious inflammatory diseases while increase of complement activity was characteristic of leukosis exacerbation.
Subject(s)
Complement System Proteins/analysis , Leukemia, Lymphocytic, Chronic, B-Cell/blood , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/blood , Leukemia, Myeloid, Acute/blood , Multiple Myeloma/blood , Humans , PrognosisABSTRACT
With a view to increase the accuracy of the differential diagnosis of chronic diseases of liver--chronic persistent hepatitis and initial manifestation of hepatic cirrhosis--the method based on the determination of general bactericidal activity of neutrophils is suggested. Cytochemical reaction on cationic proteins and nitroblue tetrazolium reduction with the blood of patients having the signs of liver lesion provide data for the calculation of the integral cytochemical activity of blood neutrophils. Values fluctuating from 4.0 to 6.0 indicate hepatic cirrhosis while their exceeding 7.0 may serve as an evidence of chronic persistent hepatitis.