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1.
Cardiovasc Intervent Radiol ; 31(2): 254-9, 2008.
Article in English | MEDLINE | ID: mdl-18026794

ABSTRACT

PURPOSE: Bilateral uterine artery embolization (UAE) is considered necessary to provide effective treatment for symptomatic uterine fibroids. Occasionally, only unilateral embolization is performed, and this study evaluates these outcomes. MATERIALS AND METHODS: As part of a prospective observational study of more than 1600 patients treated with UAE since 1996, there have been 48 patients in whom unilateral embolization has been performed. This study retrospectively reviews clinical response as assessed by our standard questionnaire and radiological response assessed by either magnetic resonance imaging or ultrasound. RESULTS: Two principal groups emerged: the largest, where only the dominant unilateral arterial supply was electively embolized (30 patients); and the second, where there was technical failure to catheterize the second uterine artery as a result of anatomical constraints (12 patients). Favorable clinical response with a reduction in menorrhagia at 1 year was seen in 85.7% (18/21) of those patients with a dominant arterial supply to the fibroid(s). In contrast, in those patients where there was technical failure to embolize one uterine artery, there was a high rate of clinical failure requiring further intervention in 58.3% (7/12). Comparison of the technical failure group with the dominant uterine artery group demonstrated a statistically significant (Fisher's exact test) difference in the proportion of patients with evidence of persistent fibroid vascularity (p < 0.001) and requiring repeat intervention (p < 0.01). CONCLUSION: We conclude that unilateral UAE can achieve a positive clinical result in the group of patients where there is a dominant unilateral artery supplying the fibroid(s), in contrast to the poor results seen following technical failure.


Subject(s)
Embolization, Therapeutic/methods , Leiomyoma/therapy , Uterine Neoplasms/therapy , Uterus/blood supply , Adult , Angiography , Female , Humans , Magnetic Resonance Imaging, Interventional , Retrospective Studies , Surveys and Questionnaires , Treatment Outcome , Ultrasonography, Interventional
2.
Cardiovasc Intervent Radiol ; 30(3): 415-8, 2007.
Article in English | MEDLINE | ID: mdl-17278034

ABSTRACT

The purpose of the study was to report our experience of the management of complications following the insertion of a peritoneovenous shunt for intractable malignant ascites. From June 1999 to January 2006, 26 patients underwent insertion of a peritoneovenous shunt for ascites by interventional radiologists. We have used ultrasound and shuntography to assist in the diagnosis of the cause of shunt blockage. Successful techniques for the restoration of the shunt function include port- pumping, stripping of any fibrin sheath, and revision of either the venous or peritoneal catheter. The procedure was initially successful in all patients with continued patency until death in 17. A further four patients are still alive with a functioning shunt. There was one rapid postprocedure death resulting from pulmonary edema. Two patients developed pneumothorax, managed successfully with either a chest drain or aspiration. Shunt dysfunction occurred eight times in seven patients. There were five successful revisions in four patients. Overall, shunt patency has been maintained in 80.1% of patients. Shunt dysfunction is seen in a significant number of patients, but successful revision of the shunt can be achieved in the majority.


Subject(s)
Breast Neoplasms/surgery , Equipment Failure , Graft Occlusion, Vascular/therapy , Ovarian Neoplasms/surgery , Pancreatic Neoplasms/surgery , Peritoneovenous Shunt/methods , Postoperative Complications/therapy , Radiography, Interventional/methods , Adult , Aged , Angiography, Digital Subtraction , Female , Fluoroscopy , Graft Occlusion, Vascular/diagnosis , Humans , Male , Middle Aged , Paracentesis , Postoperative Complications/diagnosis , Ultrasonography, Doppler
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