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Int J Immunogenet ; 44(1): 32-34, 2017 Feb.
Article in English | MEDLINE | ID: mdl-27987261

ABSTRACT

The confirmation of novel allele HLA-B*35:279 in a family of a leukaemia patient with Western Asia origin is reported. Moreover, next-generation sequencing (NGS) resulted in whole-gene sequence data and revealed the inheritance of HLA-B*35:279 on the paternal haplotype.


Subject(s)
Alleles , Amino Acid Substitution , HLA-B35 Antigen/genetics , Leukemia, Myeloid, Acute/genetics , Point Mutation , Asian People , Exons , Gene Expression , HLA-B35 Antigen/immunology , Hematopoietic Stem Cell Transplantation , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , Leukemia, Myeloid, Acute/immunology , Leukemia, Myeloid, Acute/pathology , Leukemia, Myeloid, Acute/therapy , Male , Middle Aged , Pedigree , Transplant Recipients
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