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Rev Med Chir Soc Med Nat Iasi ; 116(3): 692-9, 2012.
Article in English | MEDLINE | ID: mdl-23272512

ABSTRACT

AIM: To evaluate the prevalence of steatosis and to assess its correlations with the classical cardiovascular (CV) risk factors, components of metabolic syndrome (MS) in a rural population. MATERIAL AND METHODS: A sample of 254 subjects was enrolled in the study. Collected data included: age, gender, complete medical history, anthropometric and blood pressure (BP) measurements. The biological evaluation included metabolic and hepatic parameters. Ultrasound evaluation of steatosis relied on the criteria of the National Health and Nutrition Examination Survey (NHANES) III. RESULTS: Two thirds of the study population were obese or overweight (64.96%); 32.66% had systolic BP and 27.16% diastolic BP levels higher than normal. 38% of the subjects had abnormal fasting blood glucose levels, 14.56% having glycated hemoglobin (HbA1c) values corresponding to pre-diabetes, and 9.84% to overt diabetes; 8% had low HDL-cholesterol and 14.96% high triglycerides (Tg) levels. MS was present in 50.8% of individuals. Only 10.8% of all subjects did not have an ultrasound appearance of steatosis; 28.8% had moderate and 32% severe steatosis. There were statistically significant differences in subjects with steatosis vs. subjects without steatosis with regard to body mass index (BMI), WC, presence of MS, and BP and Tg levels, but not to ALAT, ASAT and GGT values. CONCLUSIONS: The important prevalence of obesity, fasting hyperglycamia, steatosis and MS shows a particularly metabolic fragile population; early diagnosis and interventional strategies are mandatory.


Subject(s)
Cardiovascular Diseases/complications , Fatty Liver/complications , Metabolic Syndrome/complications , Obesity/complications , Adult , Aged , Biomarkers/blood , Blood Pressure Determination , Body Mass Index , Cardiovascular Diseases/blood , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/etiology , Cardiovascular Diseases/physiopathology , Cholesterol, HDL/blood , Cross-Sectional Studies , Early Diagnosis , Fatty Liver/blood , Fatty Liver/epidemiology , Fatty Liver/physiopathology , Female , Glucose Tolerance Test/methods , Glycated Hemoglobin/metabolism , Humans , Male , Metabolic Syndrome/blood , Metabolic Syndrome/epidemiology , Metabolic Syndrome/physiopathology , Middle Aged , Non-alcoholic Fatty Liver Disease , Obesity/blood , Obesity/epidemiology , Obesity/physiopathology , Overweight/complications , Prevalence , Risk Assessment , Risk Factors , Romania/epidemiology , Rural Population/statistics & numerical data , Sampling Studies , Triglycerides/blood
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