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On the utility of data from the International HapMap Project for Australian association studies.

Stankovich, Jim; Cox, Charles J; Tan, Rachel B; Montgomery, Douglas S; Huxtable, Stewart J; Rubio, Justin P; Ehm, Margaret G; Johnson, Laura; Butzkueven, Helmut; Kilpatrick, Trevor J; Speed, Terence P; Roses, Allen D; Bahlo, Melanie; Foote, Simon J.

Hum Genet ; 119(1-2): 220-2, 2006 Mar.

Article in English | MEDLINE | ID: mdl-16404587

ABSTRACT

We compare patterns of linkage disequilibrium (LD) for 633 SNPs in two regions between samples collected in two Australian states and HapMap samples collected from Utah residents of Northern and Western (NW) European ancestry (CEU). Patterns of LD in the Australian and HapMap samples are similar, and tag SNPs chosen using HapMap genotypes perform almost as well on Australian samples as tags chosen using Australian genotypes.

Subject(s)

Linkage Disequilibrium , Polymorphism, Single Nucleotide/genetics , Europe/ethnology , Genetics, Population , Genotype , Humans , Tasmania , Utah , Victoria

ABSTRACT

Subject(s)

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