Subject(s)
Gastrointestinal Neoplasms/therapy , Lymphoma, Non-Hodgkin/therapy , Adult , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Combined Modality Therapy , Cyclophosphamide/administration & dosage , Doxorubicin/administration & dosage , Female , Fluorouracil/administration & dosage , Humans , Male , Middle Aged , Mitomycin , Mitomycins/administration & dosage , Prednisone/administration & dosage , Vincristine/administration & dosageSubject(s)
Lung Neoplasms/pathology , Lung/pathology , Adult , Aged , Cytological Techniques , Diagnosis, Differential , Female , Humans , Intraoperative Care , Lung Neoplasms/surgery , Male , Middle AgedABSTRACT
Clinical characteristics and response to therapy of 7 patients with primary non-Hodgkin's lymphoma of the stomach and 1 patient with double malignancy are analysed. All patients but one were gastrectomized and subjected to the chemotherapy (COP, CHOP or leukeran + prednison) programme. In 3 patients (2 with lymphocytic lymphoma and 1 with lymphoplasmocytic lymphoma) no recurrence occurred in the course of the observation time ranging from 18 to 20 months. In one patient with centrocytic lymphoma extra-abdominal recurrence was successfully treated with leukeran + prednison. 4 patients (2 with immunoblastic lymphoma and 1 with lymphoplasmocytic lymphoma) with abdominal or extra-abdominal recurrence died after a period ranging from 4 to 29 months despite more aggressive therapy with CHOP programme. Opinions concerning pathogenesis and treatment strategy of those lymphomas are presented too.
Subject(s)
Lymphoma, Non-Hodgkin/pathology , Stomach Neoplasms/pathology , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Combined Modality Therapy , Female , Humans , Lymphoma, Non-Hodgkin/drug therapy , Male , Middle Aged , Stomach/pathology , Stomach Neoplasms/drug therapy , Stomach Ulcer/pathologySubject(s)
Asthma/drug therapy , Levamisole/therapeutic use , Adjuvants, Immunologic , Adult , Asthma/immunology , Female , Humans , Immunity, Cellular/drug effects , Male , Middle AgedSubject(s)
Alopecia Areata/immunology , B-Lymphocytes/immunology , T-Lymphocytes/immunology , Adult , Female , Humans , Leukocyte Count , Male , Middle AgedABSTRACT
Since corticosteroids are known to be a potent factor redistributing the peripheral blood lymphocytes to other body compartments, we estimated the sub-populations of T and B lymphocytes in peripheral blood of steroid dependent asthma patients. In twenty steroid-treated asthma patients and eighteen healthy blood donors the percentage and absolute number of lymphocytes forming spontaneous rosettes with sheep red blood cells ("early" and "late" T lymphocyte marker) and mouse red blood cells (B lymphocyte marker) were determined. The asthma patients were treated with 40 or 60 mg of triamcinolone acetonide (Kenalog) i.m. for at least one year or more prior to the study. No statistically significant differences were observed in lymphocyte subpopulations between steroid-treated asthma patients and healthy blood donors.
