ABSTRACT
PURPOSE: To assess retinal electrophysiologic dysfunction in patients with central serous chorioretinopathy (CSC) with multifocal electroretinograms (mfERGs) and full-field electroretinograms (Full-field ERG). METHODS: 24 patients with unilateral CSC and 24 age-similar control group underwent fundus exam, fluorescein angiography, mfERG and full-field ERG. The results of testing of patients with CSC in the affected and fellow eyes were compared with the age-similar normal controls. RESULTS: All of the patients had central macular detachments in the affected eyes, while the fellow eyes were normal. In fluorescein angiography, all of the patients had small, focal hyperfluorescent leak in early phase in the affeted eyes, while the fellow eyes were nonspecific findings. The results of full-field ERG were not significantly different between unilateral CSC patient and normal control group. In mfERG, amplitude of both affected and fellow eyes were significantly decreased in the entire test field of retina comparing with normal controls (P<0.05), while implicit time increased (P<0.05). CONCLUSIONS: Not only affected eyes but fellow eyes of the patients with CSC had abnormal responses in the first order kernel. These results suggested that not only affected but also fellow eyes possibly had underlying pathologic condition as abnormal chorioidal circulation. mfERG may be useful in evaluating the retinal function of affected and fellow eyes with CSC patients.
