ABSTRACT
A case of focal nodular hyperplasia of the liver in childhood (FNH or NRC) is reported; a conservative approach is usually preferred in this disease when the diagnosis is surely identified, and a follow-up for some years is recommended. Despite the increased accuracy of modern imaging methods none of them, singly or together, is able to differentiate a malignant lesion with certainty and histological confirmation is mandatory. In the case described a laparotomy frozen section was performed but it was not possible to make a diagnosis and the liver mass was removed. The patient had a complete relief of symptoms with no evidence of recurrence in the follow-up. A review of the literature has been made, trying to point out this disease and its treatment.
Subject(s)
Abdominal Pain/etiology , Liver Neoplasms/complications , Adolescent , Female , Humans , Hyperplasia/complications , Hyperplasia/pathology , Hyperplasia/surgery , Liver Neoplasms/pathology , Liver Neoplasms/surgery , Magnetic Resonance Imaging , RecurrenceABSTRACT
Serum IgG sub-classes levels were measured by radial immunodiffusion with policlonal antibodies in 26 children aged 2 years to 8 years, affected with respiratory recurrent infections. These subjects were controlled and compared with normal children values for age groups. In 10 patients a deficit of IgG sub-classes levels was found, in 7 patients an increase level for IgG1 was detected. These data must be taken in account defining IgG-sub-classes deficiencies in children with respiratory recurrent infection.
Subject(s)
Immunoglobulin G/immunology , Respiratory Tract Infections/immunology , Age Factors , Child , Child, Preschool , Enzyme-Linked Immunosorbent Assay , Female , Humans , Male , RecurrenceABSTRACT
Fourteen children affected with allergic disease, from 8 months to 7-years-old, were studied; three children had Bronchial asthma, one child Bronchial asthma and rhinitis, one child recurrent laryngospasm, six children atopic dermatitis, two children diarrhoea, one abdominal pain. In all patients cow's milk and egg were the most common offending foods. Total IgE serum level, IgE serum specific, Prick test and ALCAT test (the test predicts food which would produce a problem) were investigated. A comparison among the different laboratory methods for food allergy diagnosis was analyzed.
Subject(s)
Food Hypersensitivity/diagnosis , Asthma/etiology , Child , Child, Preschool , Dermatitis, Atopic/etiology , Enzyme-Linked Immunosorbent Assay , Female , Food Hypersensitivity/complications , Humans , Immunoglobulin E/blood , Infant , Male , Rhinitis, Allergic, Perennial/etiologyABSTRACT
Most instance of drug-induced renal disease are probably due to direct toxicity; the most common immunologically mediated lesion of the kidney due to drugs appears to be interstitial nephritis-fever, skin rash, eosinophilia, eosinophiluria frequently accompany the renal symptoms. One case we report due to ceftriaxone; the disease subsided completely when the treatment with the drug has been stopped.
Subject(s)
Ceftriaxone/adverse effects , Nephritis, Interstitial/chemically induced , Child , Humans , Kidney Function Tests , Male , Nephritis, Interstitial/diagnosisABSTRACT
Subcutaneous nodules of the rheumatic type can occur in patients without other evidence of rheumatic disease. Nodules are characterized by subcutaneous location with predilection for pretibial regions and scalp, occasional large size, spontaneous regression and frequent recurrence. Sometimes lesion biopsy may be usefull for confirmation of the clinical diagnosis; etiology is unknown, therapy is unnecessary. One asymptomatic child with benign rheumatoid nodules is described by the Authors.
