1.
Nucleosides Nucleotides Nucleic Acids
; 26(10-12): 1225-9, 2007.
Article
in English
| MEDLINE
| ID: mdl-18066757
ABSTRACT
A number of 5'-and 3'-glycoconjugates of the oligonucleotide (5')d(TGGGAG)(3') have been synthesized, exploiting fully automated, online phosphoramidite-based solid phase strategy, as potential anti-HIV-1 agents. The thermodynamic stability of the resulting quadruplexes has been investigated by thermal denaturation studies, via a detailed CD Q1 analysis.