[The specifics of clinical course and pathogenesis of mild brain injury in children]. / Osobennosti klinicheskogo techeniia i patogeneza legkoi cherepno- mozgovoi travmy u detei.

Clinical peculiarities and pathogenesis of mild cerebrocranial trauma (CCT) in 106 children aged 1-14 years were studied. The boys made up 66.03% of this group. Neurologic, immunologic (CIC, immunoglobulins A, M, G) and biochemical (level of thyobarbituric acid, TBA-active products) investigations were performed on day 1 and 10 after the trauma. There were increased levels of CIC and TBA-active products on the 1st day, while after the recovery (to the 10th day) elevation of these indices was less pronounced pronounced. The authors made a conclusion about participation of both immunologic and biochemical alterations in pathologic process resultant in disorders of metabolism and microcirculation. Thus, such children need longer pathogenetic therapy to prevent development of neurologic complications in the remote period of CCT.