1.
Biokhimiia
; 56(4): 747-52, 1991 Apr.
Article
in Russian
| MEDLINE
| ID: mdl-1912076
ABSTRACT
It was found that incorporation into phosphatidylcholine monolamellar liposomes of prostaglandin E1 or its synthetic analog containing a phenol group instead of a carboxyl one leads to a significant decrease of the liposome permeability for glucose. The prostaglandin E1 analog appeared to be more membrane-active one. The data obtained were compared with the experimentally established changes in the monolayer compressibility. The experimental results are discussed in terms of a theoretical model which entails that this permeability is proportional to the number of dynamic whose diameter markedly exceeds the molecular size of glucose.
Subject(s)
Alprostadil/metabolism , Glucose/metabolism , Liposomes/metabolism , Phosphatidylcholines/metabolism , Permeability
2.
Dokl Akad Nauk SSSR
; 299(3): 751-4, 1988.
Article
in Russian
| MEDLINE
| ID: mdl-2841082