ABSTRACT
State of microbiocenosis of large intestine in rats and furo subjected to constant combined irradiation has been studied in full-scale experiments in the emergency rooms of the Chernobyl NPP and in the nearest zone of its effect. The higher diversity of microflora (as compared to initial one), sharp increase of the amount of Candida genus fungi, a decrease of the number of bifidobacteria and increase of the amount of conditionally pathogenic flora were observed in rats with the dose of external irradiation of 1.43 Gr absorbed for 14 days. The expressed associative character of disbioses is distinctly traced. In furo affected by the radion exceeding the background level feeding with products contaminated by radionuclides leads to changes whose individual character corresponds to the picture of disbiosis under radiation injury.
Subject(s)
Environmental Exposure/adverse effects , Intestine, Large/microbiology , Intestine, Large/radiation effects , Power Plants , Radioactive Hazard Release , Radioactive Pollutants/adverse effects , Animals , Feces/microbiology , Male , Rats , UkraineABSTRACT
The association of plaque production under bentonite overlay with the cycle of intracellular reproduction of enteroviruses and the dynamics of the membrane potential of infected cells was studied. It was shown that by the time of termination of the intracellular enterovirus reproduction cycle (4 1/2-5 hours postinfection) bentonite particles were torn away from the cell surface. At the same time the membrane potential of the host cell began to decline progressively. The data obtained explain the character of morphology of virus plaques under bentonite overlay.
