[Cytobiochemical characteristics of the function of pulmonary alveolar macrophages during development of immune reactions after exposure to chemical air pollutants]. / Tsitobiokhimicheskaia kharakteristika funktsional'nogo sostoianiia al'veoliarnykh makrofagov legkikh v protsesse razvitiia zashchitnykh reaktsii organizma pri vozdeistvii khimicheskikh zagriaznitelei atmosfernogo vozdukha.

Based on an analysis of correlations between variation in the amount of alveolar macrophages of rat lungs and activity of enzymes localized in these cells (acid phosphatase, beta-galactosidase, beta-glucosidase, lactate dehydrogenase), the cytobiochemical changes in the function of pulmonary alveolar macrophages have been defined with the use of a model of permanent inhalation exposure to sulfur dioxide. The use of the model enables the dilimitation of the stages of defence-compensatory reactions and their transition to an unfavourable biological effect. The results obtained may serve as a theoretical basis for recommending a wider experimental application of the tests in question during regulation of environmental factors.