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1.
Vopr Virusol ; 54(4): 32-6, 2009.
Article in Russian | MEDLINE | ID: mdl-19708553

ABSTRACT

The paper presents the results of studying genital squamous epitheliocytes from human papillomavirus-infected female patients by cytology and atomic force microscopy. The squamous epitheliocytes with and without cytomorphological signs of papillomavirus infection (koilocytosis, dyskeratosis, parakeratosis, hyperkeratosis) have been compared. Examining the surface of the squamous epithelium has yielded quantitative characteristics of infection-induced surface changes.


Subject(s)
Epithelial Cells/pathology , Genitalia, Female/pathology , Microscopy, Atomic Force/methods , Papillomaviridae , Papillomavirus Infections/pathology , Vulvovaginitis/pathology , Adult , Epithelial Cells/ultrastructure , Female , Genitalia, Female/ultrastructure , Humans , Microscopy, Electron, Scanning , Papillomavirus Infections/complications , Vulvovaginitis/virology
2.
Article in Russian | MEDLINE | ID: mdl-3223149

ABSTRACT

Clinical and hormonal indices of androgenic activity were compared in 118 males chronically intoxicated with alcohol. The population was divided into two groups with respect to their clinical and hormonal androgenic indices: 76 patients with (Group 1), and 46 patients without (Group 2) androgenic insufficiency. Distinct signs and syndromes of alcohol addiction were shown to correlate with the extent of cross-regulation impairment within hypothalamo-hypophyseo-gonadal system. This was particularly derived from comparison of clinical picture of chronic alcohol intoxication and hormone activity in the groups. Conventional therapy failed to restore the neuroendocrine indices that was apparently due to inhibition of cross-regulation links in the hypothalamo-hypophyseo-gonadal system at several stages of alcohol addiction.


Subject(s)
Alcoholism/diagnosis , Endocrine System Diseases/diagnosis , Neurosecretory Systems , Adult , Alcoholism/blood , Alcoholism/complications , Androgens/deficiency , Endocrine System Diseases/blood , Endocrine System Diseases/etiology , Ethanol/adverse effects , Humans , Male , Middle Aged , Neurosecretory Systems/physiopathology , Substance Withdrawal Syndrome/blood , Substance Withdrawal Syndrome/diagnosis
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