[The activity of the lipid peroxidation processes in the mucosa of the rat small intestine and its morphofunctional state under acute irradiation and the administration of combined preparations created on a base of highly dispersed silica]. / Aktivnost' protsessov perekisnogo okisleniia lipidov v slizistoi obolochke tonkoi kishki krys i ee morfofunktsional'noe sostoianie v usloviiakh ostrogo oblucheniia i vvedeniia kombinirovannykh preparatov, sozdannykh na osnove vysokodispersnogo kremnezema.

Morphofunctional and biochemical studies were carried out on bastard male rats (weight 200-240 g). The results showed that X-ray irradiation had induced structural alterations and elevation of lipid peroxidation in small intestine. Using of complex preparations defended this organ against pathological damages. The first preparation provided rat organisms with 100 ml/kg of silica, 2 mg/kg of beta-carotene, 30 mg/kg of alpha-tocopherol and 0.2 mg/kg of natrium selenite. The second preparation provided 100 mg/kg of silica, 10 mg/kg of dry Rhodiola extract, 0.1 mg/kg of tincture of Lagochilus [correction of Ladohilli] inebrians and 0.05 ml/kg of tincture of Aralia mandshurica. The third preparation provided organism with 100 mg/kg of silica and 20 mg/kg of thiobenzimidazole derivative. All these preparations had produced marked pharmacological effect.

[The immunomorphological characteristics of a focal staphylococcal infection against a background of long-term exposure to low doses of simazine]. / Immunomorfologicheskaia kharakteristika ochagovoi stafilokokkovoi infektsii na fone dlitel'nogo vozdeistviia malykh doz simazina.

State of immunologic and nonspecific resistance of the organism, ultra- and histostructure of the thymus, histopathology of the wall of experimental staph abscess reproduced in animals given low doses of the herbicide simazine for a long time have been studied. It is established that simazine induced the immunodeficiency state underlain by pathologic changes in the thymus. Against this background experimental abscesses developed more rapidly, alterative and exudative processes in their wall proceeding more intensively and proliferative ones--attenuating. This provides prolongation of the abscesses healing phase for an indefinite time and chronization of the process.

[Ultrastructural changes in the adenohypophysis-thyroid system in chronic poisoning by the herbicide linuron]. / Ul'trastrukturnye izmeneniia v adenogipofizarno-tireoidnoi sisteme pri khronicheskom otravlenii gerbitsidom linuronom.

Ultrastructural adenohypophysis-thyroid system investigation of Wistar male rats under conditions of chronic poisoning by Linuron herbicide and administration of thymohemin immunomodulator was performed. The release of thyrocyte fragments into the vascular lumen, electron-dense deposits in the area of vascular basal membrane, dilatation of endoplasmic reticulum cisternae as well as inhibition of Golgi complex in thyrocytes are observed in the thyroid exposed to Linuron; in the adenohypophysis under the same conditions swelling and splitting of microvessel basal membrane as well as the increase of biosynthetic and secretory thyrotrophic function can be seen. Thymohemin reduces the degree of degenerative processes in the thyroid gland.