ABSTRACT
By fibrocolonoscopy, fibrocolonoscopic biopsy, polypectomy, operation resp., one hundred and eight true polypi in the colon of 75 patients were studied, grouped according to localization: in caecum -- 2.8 per cent, in ascending colon -- II. I per cent, transverse colon -- 13.9 per cent, descending colon -- 19.4 per cent, in sigmoid colon -- 40.8 per cent and in rectum -- 12 per cent. Endoscopically they were grouped as follows: adenomatous -- 91.7 per cent and villous -- 8.3 per cent and after the pathohistological examination as: adenomatous 73.3 per cent, adenovillous -- 17.2 per cent and villous -- 9.5 per cent. In 40 (52.8%) of the cases, well differentiated polypi were concerned (I grade); in 30 (38%) -- moderately differentiated polypi (II grade) and in 5 (6.5%) -- poorly differentiated polypi (III grade). The studies revealed that the pathohistological examination was a method, specifying the morphological structure of polypus, determining the therapeutic behaviour of the clinicists. Fibrocolonoscopic polyrectomy solves the problem of diagnostics and treatment of the true polypi, contributing to the prophylaxis of colon carcinoma.
Subject(s)
Colonoscopy , Intestinal Polyps/pathology , Intestine, Large/pathology , Adult , Aged , Biopsy , Cecal Neoplasms/pathology , Female , Fiber Optic Technology , Humans , Intestinal Polyps/classification , Male , Middle Aged , Rectal Neoplasms/pathology , Sigmoid Neoplasms/pathologyABSTRACT
Three hundred sixty two patients with rectosigmoid cancer are examined by rectoromanoscopy and biopsy in order to establish those of them with manifestations of a proceeding precancer process. Cancer, originated on the base of single polypus was established in 50,94 per cent and 7,54 per cent in relation with preceeding generalized polyposis, in 30,19 per cent malignant villose tumor is concerned, in 4,71 per cent -- cancer, originated on the base of preceeding ulcerohemorrhagic proctocolitis and in only 1,91 per cent -- malignant chronic fibrosclerosed hemorrohoids. Precancer process is established in 29,29 per cent in all of the examined 362 patients with rectosigmoid cancer and in 70,71 per cent of the cases no manifestations of preceeding precancer disease was established, i.e. the malignancy ratio with established precancerosis towards malignancy without established precancerosis is approximately 1 : 2,5. That fact requires acute attention in all cases with established precancerosis of the terminal segment of large intestine, treatment without delay and dispensary control.
Subject(s)
Precancerous Conditions/pathology , Rectal Neoplasms/etiology , Sigmoid Neoplasms/etiology , Adult , Aged , Biopsy , Female , Humans , Male , Middle Aged , Rectal Neoplasms/epidemiology , Rectal Neoplasms/pathology , Sigmoid Neoplasms/epidemiology , Sigmoid Neoplasms/pathology , SigmoidoscopyABSTRACT
Aiming at the establishment of the type and incidence of morphological and tonometric large intestine changes post cholecystectomy--64 patients were examined, 36 aged up to 50 and 28 over 50 by means of rectoromanoscopy, transrectoscopic biopsy, X-ray examination (passage and irigoscopy), balloon signography and anal tonometry. Morphological changes--catarrhal type (34.38%) were established to originate often in large intestine post cholecystectomy. Tonometric changes were observed in 56.25%. They are: hypertonic hypokinesia (45.32%) and hyperkinesia (10.93%). All patients with morphological changes are also and with tonometric disturbances. Ergo, 21.87% of the patients are with tonometric disturbances without pathomorphological changes. In the correlation of the morphological with tonometric changes, the catarrhal changes with hypertonic hypokinesia were established to be the most frequently met morbid combination and considerably more rarely--"catarrhal changes with hyperkinesia". Normotonia and normokinesia are most often found in cases with normal mucosa and considerably less rarely--hypertonic hypokinesia. The morphological as well as the tonometric changes are more frequent with age advancing of the patients and the growth of the time post cholecystectomy. Subjective complaints are reported from 56.25% of the patients. The most frequently met are feeling of heaviness in the abdomen, more rarely meteorism and rumble of the intestines and most rarely--pains along the large intestine. Objectively pain findings in the physical examination of abdomen and large intestines are established in 56.25% of the patients. Meteorism is most frequently established and relatively more rarely spastic large intestine and pain with its palpation (almost with equal frequency). Defecation is normal in 29.69% of the patients. The rest complain more often of diarrhea (45.32%) and more rarely of constipation (25%).
