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Recenti Prog Med ; 100(7-8): 352-5, 2009.
Article in Italian | MEDLINE | ID: mdl-19725475

ABSTRACT

UNLABELLED: The aim of this study is to evaluate if plasma fibrinogen levels could correlate with carotid lesions. METHODS: We investigated the plasmatic levels of fibrinogen in 100 patients with asymptomatic carotid lesions, examined at ultrasound, and with at least one traditional cardiovascular risk factor. RESULTS: We found a significant correlation between plasma fibrinogen levels and severity of carotid lesions: intima-media thickness (p < 0.001), stenosis <70% (p < 0.002), stenosis 270% (p < 0.001). CONCLUSIONS: Beyond traditional cardiovascular risk factors, high plasmatic levels of fibrinogen significantly correlate with the thickness of carotid wall in asymptomatic subjects.


Subject(s)
Carotid Artery Diseases/diagnosis , Carotid Artery, Common/pathology , Fibrinogen/metabolism , Aged , Aged, 80 and over , Biomarkers/blood , Blood Coagulation Tests , Carotid Artery Diseases/blood , Carotid Artery Diseases/diagnostic imaging , Carotid Artery Diseases/pathology , Carotid Artery, Common/diagnostic imaging , Female , Humans , Male , Medical Records , Middle Aged , Predictive Value of Tests , Retrospective Studies , Risk Assessment , Severity of Illness Index , Tunica Intima/pathology , Tunica Media/pathology , Ultrasonography
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