ABSTRACT
Corticosteroids were administered in 120 patients with active pulmonary tuberculosis during the morning hours every other day in association with tuberculostatic agents. It was found that corticosteroids in a dose similar to 15 mg of prednisolone did not influence the efficacy of antibacterial agents while an increase to 20 mg used for not less than 2 months increases the treatment efficacy to 83.3% and over 3 months--to 89.5%.
Subject(s)
Adrenal Cortex Hormones/administration & dosage , Tuberculosis, Pulmonary/drug therapy , Adult , Antitubercular Agents/therapeutic use , Drug Evaluation , Drug Therapy, Combination , Female , Humans , Male , Mycobacterium tuberculosis/isolation & purification , Time Factors , Tuberculosis, Pulmonary/microbiologySubject(s)
Immunoglobulin G/analysis , Tuberculin Test , Tuberculosis, Pulmonary/immunology , Adult , Aged , Female , Humans , Lymphocyte Activation , Male , Middle Aged , Prognosis , RecurrenceABSTRACT
A cytochemical study of RNA was carried out in gonadotropic basophils and oxyphils of adenohypophysis of albino nonstrain rats during DMBA-induced mammary cancer growth. A stage character is found for changes in the RNA content depending on the mammary carcinogenesis phase. This shows that DMBA carcinogenic action besides a direct damage effect on the mammary gland is realized to a considerable extent through the endocrine system.