ABSTRACT
OBJECTIVE: To study the diagnostic importance of a new Indis software package for the postprocessing of the results of radionuclude examinations (Center for Information and Diagnostic Systems, St. Petersburg, Russia) when analyzing the results of lacrimal scintigraphy. MATERIAL AND METHODS: Dynamic lacrimal scintigraphy was carried out in 6 volunteers (12 eyes) and 20 patients (32 years) with dacryostenosis. The examined Indis program and the known Syngo program (Siemens, Germany) were used to calculate the elimination half-life of a radiopharmaceutical from the interest region corresponding to the whole ocular surface. The time taken to postprocess the results of the examination was also determined. RESULTS: When calculations were made using the Indis program and the Syngo system, the elimination half-lives of a tracer in the volunteers was 6.57 ± 2.46 and 7.54 ± 3.21 min, respectively. These in the patents with dacryostenosis were 69.39 ± 65.52 and 74.85 ± 64.59 min. With these programs, the times taken for postprocessing were 12.3 ± 4.2 and 26.3 ± 7.9 min, respectively. CONCLUSION: The investigation showed the practical significance of the Indis software package in processing the data of lacrimal scintigraphy. The calculations made with the Indis program correspond to those made with the known Syngo program. The convenience and ergonomics of the program can precisely identify the region of interest. The economic justification of the system is associated with the shorter time taken to postprocess and interpret the results of lacrimal scintigraphy. The Indis software package may be recommended for use in the examination and treatment monitoring in patients with abnormal lacrimaton.
Subject(s)
Electronic Data Processing/methods , Lacrimal Apparatus/diagnostic imaging , Lacrimal Duct Obstruction/diagnostic imaging , Software Design , Adult , Aged , Cross-Over Studies , Female , Humans , Lacrimal Apparatus/metabolism , Lacrimal Duct Obstruction/metabolism , Male , Middle Aged , Prospective Studies , Radionuclide Imaging , Radiopharmaceuticals/pharmacokinetics , Young AdultABSTRACT
OBJECTIVE: To explore the capabilities of single-photon emission computed tomography (SPECT) in combination with x-ray computed tomography (SPECT/CT) in the study of the anatomy and drainage function of lacrimal passages. MATERIAL AND METHODS: Twelve scans were carried out in 6 healthy volunteers and in patients with different lacrimal drainage disorders (dacryostenoses, varying obstructive lacrimal passage, dacryocystitis and post-dacryocystorhinostomy). Sodium pertechnetate (99mTc) solution and a radiocontrast agent were instilled into the conjunctival sac during the study. RESULTS: SPECT is an objective procedure to study lacrimal drainage function. It cannot provide data on the anatomic structure of lacrimal passages and determine the location of their stenosis or obstruction. SPECT/CT makes it possible to simultaneously obtain information on the anatomic structure of lacrimal passages, to visualize the sites of their pathological changes, and to evaluate the drainage function of lacrimal passages.
Subject(s)
Lacrimal Apparatus Diseases/diagnosis , Lacrimal Apparatus , Tomography, Emission-Computed, Single-Photon/methods , Tomography, X-Ray Computed/methods , Constriction, Pathologic/diagnostic imaging , Contrast Media , Female , Humans , Lacrimal Apparatus/diagnostic imaging , Lacrimal Apparatus/physiopathology , Lacrimal Apparatus Diseases/classification , Lacrimal Apparatus Diseases/physiopathology , Male , Middle Aged , Radiographic Image Enhancement , Radiopharmaceuticals , Reproducibility of ResultsABSTRACT
The article presents the results of a monocentric randomized open prospective study conducted from 2008 to 2013. Lacrimal intubation with Mini-Monoka and Monoka silicone stents (mono- or bicanalicular) or with SRS and Ritleng ("FCI", France) stents for dacryostenosis of different localization was performed in 151 patients (203 eyes). The follow-up period was 12 months after the extubation. Patient examination and monitoring included collection of subjective Munk scores for epiphora, lacrimal scintigraphy and bulbar hyperemia evaluation. Though all interventions were proved to be effective, the authors came to the conclusion that, bicanalicular Mini-Monoka and Monoka stents were associated with fewer complications as compared with bicanalicular SRS and Ritleng stents.
Subject(s)
Dacryocystorhinostomy , Lacrimal Apparatus , Lacrimal Duct Obstruction , Minimally Invasive Surgical Procedures , Postoperative Complications/prevention & control , Stents , Adult , Aged , Comparative Effectiveness Research , Dacryocystorhinostomy/adverse effects , Dacryocystorhinostomy/methods , Female , Follow-Up Studies , Humans , Lacrimal Apparatus/diagnostic imaging , Lacrimal Apparatus/physiopathology , Lacrimal Apparatus/surgery , Lacrimal Duct Obstruction/diagnosis , Lacrimal Duct Obstruction/physiopathology , Male , Middle Aged , Minimally Invasive Surgical Procedures/adverse effects , Minimally Invasive Surgical Procedures/methods , Monitoring, Physiologic/methods , Moscow , Postoperative Complications/etiology , Quality Improvement , Radionuclide Imaging , Stents/standards , Stents/trends , Treatment OutcomeABSTRACT
The article presents the results of a long-term study on application of cytological examination in dacryology. A total of 194 patients (288 eyes) with dacryostenosis, dacryocystitis, and obliteration of lacrimal canaliculi orifices were assessed. Pathogenically oriented conservative treatment, in accordance with the results of clinical, instrumental, and cytological examination, was given to all patients with dacryostenosis. Patients with dacryocystitis and lacrimal canaliculi orifice obliteration received surgical treatment: microendoscopic dacryocystorhinostomy, transcanalicularis laser dacryocystorhinostomy, and microendoscopic canaliculocystorhinostomy. Cytological examination, among other methods, was used to evaluate treatment results. The method has been demonstrated as objective and can be included into the assessment and follow-up algorithm for patients with lacrimal ducts pathology.
