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[Wars of cells with the use of nanoweapons].

Iashin, D V; Sashchenko, L P; Gnuchev, N V; Georgiev, G P.

Biofizika ; 56(5): 857-62, 2011.

Article in Russian | MEDLINE | ID: mdl-22117442

ABSTRACT

Some mechanisms of the antitumor action of the protein Tag7 have been considered, and three scenarios of the manifestation of cytotoxic effects during the formation of its complex with other proteins have been considered.

Subject(s)

Cytokines , HSP70 Heat-Shock Proteins , Immunotherapy , Neoplasms/therapy , Animals , CD8-Positive T-Lymphocytes/immunology , Clinical Trials as Topic , Cytokines/immunology , Cytokines/metabolism , Cytotoxins/immunology , Cytotoxins/metabolism , HSP70 Heat-Shock Proteins/immunology , HSP70 Heat-Shock Proteins/metabolism , Humans , Immunity, Innate , Mice , Multiprotein Complexes/immunology , Multiprotein Complexes/metabolism , Neoplasms/immunology , Protein Binding

[Molecular mechanisms of cytolytic processes induced by human LAK cells]. / Molekuliarnye mekhanizmy tsitoliticheskikh protsessov, indutsirovannykh LAK-kletkami cheloveka.

Sashchenko, L P; Dukhanina, E A; Luk'ianova, T I; Kabanova, O D; Romanova, E A; Shatalov, Iu V; Iashin, D V; Gnuchev, N V.

Mol Biol (Mosk) ; 34(5): 816-20, 2000.

Article in Russian | MEDLINE | ID: mdl-11033807

Subject(s)

Cytotoxicity, Immunologic/genetics , Killer Cells, Lymphokine-Activated/physiology , Apoptosis , Humans , Interleukin-2/pharmacology , K562 Cells , Killer Cells, Lymphokine-Activated/drug effects

[Physical contact between human erythroid cells and murine fibroblasts induces expression both secreted and membrane associated cytotoxic proteins]. / Pri fizicheskom kontakte éritroidnykh kletok cheloveka i fibroblastov myshi aktiviruetsia ékspressiia kak sekretiruemykh, tak i sviazannykh s kletochnymi membranami tsitotoksicheskikh faktorov.

Sashchenko, L P; Dukhanina, E A; Luk'ianova, T I; Romanova, E A; Iudinkova, E S; Iarovaia, O V; Iashin, D V; Razin, S V.

Dokl Akad Nauk ; 368(1): 122-4, 1999 Sep.

Article in Russian | MEDLINE | ID: mdl-10546056

Subject(s)

Cell Communication , Erythrocytes/physiology , Fibroblasts/physiology , Membrane Proteins/biosynthesis , Proteins/metabolism , Animals , Cell Membrane/physiology , Coculture Techniques , Culture Media, Conditioned/toxicity , Erythrocytes/cytology , Fibroblasts/cytology , Humans , K562 Cells , Membrane Proteins/toxicity , Mice , Proteins/toxicity

[Characteristics of cytotoxic proteins, expression of some in nonlymphoid cells is activated upon contact by cells from different organisms]. / Kharakteristika tsitotoksicheskikh belkov, ékspressiia kotorykh v nelimfoidnykh kletkakh aktiviruetsiapri kontakte kletok raznykh organizmov.

Sashchenko, L P; Dukhanina, E A; Luk'ianova, T I; Romanova, E A; Iudinkova, E S; Iarovaia, O V; Iashin, D V; Razin, S V; Gnuchev, N V.

Dokl Akad Nauk ; 367(6): 834-6, 1999 Aug.

Article in Russian | MEDLINE | ID: mdl-10520461

Subject(s)

Cell Adhesion , Cell Survival/physiology , Cytoskeletal Proteins/physiology , Animals , Antigens/immunology , Cell Line , Coculture Techniques , Cytoskeletal Proteins/chemistry , Cytoskeletal Proteins/immunology , Humans , Mice , Molecular Weight , Tumor Necrosis Factor-alpha/immunology

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