[Disbiotic conditions in patients operated and reoperated for heart defects and ischemic heart disease]. / O disbioticheskikh sostoianiiakh u bol'nykh, operirovannykh i reoperirovannykh po povodu porokov serdtsa i IBS.

Bacteriological examination of angiocardiac system, biocenosis of the intestine and upper respiratory tracts was made in 3473 patients who were to be operated or reoperated for congenital or acquired valvular defects in the presence of chroniosepsis and chronic septic endocarditis, complicated IHD. 375 patients with other diseases served control. 74 of them have undergone surgery for varicose veins of the legs. Preoperative contamination with opportunistic microflora was found in the heart, major vessels, veins of the majority of the patients. There was also dysbiosis of natural biotops. Patients with valvular defects to be reoperated 2-20 years after the initial operation on the heart had infection in the angiocardiac structures, severe dysbiosis of natural biotops, i.e. advanced dysbiosis--severe persistent condition with permanent source of endogenic infection complicated the underlying disease and bringing postoperative septic complications.

[Dynamics of accumulation of extracellular proteins of Serratia marcescens and their nuclease activity during cell growth]. / Izuchenie dinamiki nakopleniia ékstratselliuliarnykh belkov Serratia marcescens i ikh nukleaznoi aktivnosti v protsesse rosta kletok

Serratia marcescens, strain B-10 M-1, liberates an unspecific endonuclease into the extracellular nutrient solution. Two peaks of the enzyme activity were found in the cultural broth during growth of the cells. The dynamics of accumulation of protein fractions in the cultural broth was studied, and the relative electrophoretic mobility of the enzyme-active part of the proteins was established.