ABSTRACT
BACKGROUND: Alcohol consumption is a risk factor for many health problems. Mortality from causes of death wholly attributable to alcohol consumption by sex and income level was studied and trends in the 1993-2017 period were analyzed in Navarre (Spain). METHODS: Deaths due to alcohol-induced mental disorders, dependence and abuse, alcoholic cardiomyopathy, alcoholic cirrhosis and other alcoholic liver diseases, and accidental alcohol poisoning were selected through codes ICD-9 and ICD-10. Annual income that determines copayment level was used as an indicator of socioeconomic status. Mortality rates adjusted to the European standard population were calculated using the direct method and joinpoint regression was used to evaluate the temporal trend. RESULTS: A total of 441 deaths were recorded in the population aged 35-79 years. It highlights liver cirrhosis as the most common cause (77,5%). Death rates in men were ten and five times higher than in women in 1993-1997 and 2013-2017 periods, respectively. Compared to men with incomes above 18,000 , mortality rates were five times higher in the population with incomes below 18,000 . No statistically significant changes were observed in the trend of mortality rates throughout the period studied. CONCLUSIONS: Mortality by causes of death wholly attributable to alcohol has not decreased in Navarre in the last three decades, it is higher in men than in women and in the population with lower incomes.
Subject(s)
Alcohol-Induced Disorders/mortality , Income , Sex Distribution , Adult , Age Distribution , Aged , Alcoholism/mortality , Cardiomyopathy, Alcoholic/mortality , Cause of Death , Confidence Intervals , Cross-Sectional Studies , Ethanol/poisoning , Female , Humans , Liver Diseases, Alcoholic/mortality , Male , Middle Aged , Psychoses, Alcoholic/mortality , Risk Factors , Socioeconomic Factors , Spain/epidemiology , Time FactorsABSTRACT
OBJECTIVE: To determine and compare the micro topographic characteristics of dental implants submitted to different surface treatments, using scanning electron microscopy (SEM). MATERIALS AND METHODS: Implants were divided into 7 groups of 3 specimens each, according to the surface treatment used: group 1: Osseotite, BIOMET 3i; group 2: SLA surface, Institut Straumann AG; group 3: Oxalife surface, Tree-Oss implant; group 4: B&W implant surface; group 5: Q-implant surface; group 6: ML implant surface; group 7: RBM surface, Rosterdent implant. The surfaces were examined under SEM (Carl Zeiss FE-SEM-SIGMA). Image Proplus software was used to determine the number and mean diameter of pores per area unit (mm). The data obtained were analyzed with the Mann-Whitney test. A confocal laser microscope (LEXT-OLS4100 Olympus) was used to conduct the comparative study of surface roughness (Ra). Data were analyzed using Tukey's HSD test. RESULTS: The largest average pore diameter calculated in microns was found in group 5 (3.45 µm+/-1.91) while the smallest in group 7 (1.47µm+/-1.29). Significant differences were observed among each one of the groups studied (p<0.05). The largest number of pores/mm(2) was found in group 2 (229343) and the smallest number in group 4 (10937). Group 2 showed significant differences regarding the other groups (p<0.05). The greatest roughness (Ra) was observed in group 2 (0.975µm+/-0.115) and the smallest in group 4 (0.304µm+/-0.063). Group 2 was significantly different from the other groups (p<0.05). CONCLUSION: The micro topography observed in the different groups presented dissimilar and specific features, depending on the chemical treatment used for the surfaces..
ABSTRACT
Furazolidone is an antimicrobial compound used in human and veterinary medicine. The aim of this investigation was to determine its genotoxic capacity in vitro and in vivo. We used the human lymphocyte culture system to detect the effect of 2.0, 4.0, 6.0, 8.0, or 10.0 micrograms/ml, and the mouse bone marrow assay to determine the effect of 8.6, 30.0, or 75.0 mg/kg furazolidone. In both systems we determined the frequency of sister-chromatid exchanges (SCE), the cell proliferation kinetics (CPK), and the mitotic index (MI). The in vitro results showed a significant SCE increase starting from the second dose tested and a CPK and MI decrease starting from the third dose. The in vivo results showed a SCE increase with the two high doses tested, but no significant modification was found in the CPK and MI with the three doses tested in the experiment.
Subject(s)
Anti-Infective Agents, Local/toxicity , Cell Division/drug effects , Furazolidone/toxicity , Mitotic Index/drug effects , Sister Chromatid Exchange/drug effects , Animals , Bone Marrow/drug effects , Cells, Cultured , Dose-Response Relationship, Drug , Humans , Kinetics , Lymphocytes/drug effects , Male , MiceABSTRACT
It is discussed the importance of the diagnostic, prognostic and treatment design procedures in the oral rehabilitation where osseointegrated implants are used, doing a detail of the sequence to follow during this important treatment stage.
Subject(s)
Dental Implantation, Endosseous , Mouth Rehabilitation/methods , Patient Care Planning , Humans , Mouth, Edentulous/diagnostic imaging , Osseointegration , RadiographyABSTRACT
It is discussed the importance of the diagnostic, prognostic and treatment design procedures in the oral rehabilitation where osseointegrated implants are used, doing a detail of the sequence to follow during this important treatment stage.
ABSTRACT
It is discussed the importance of the diagnostic, prognostic and treatment design procedures in the oral rehabilitation where osseointegrated implants are used, doing a detail of the sequence to follow during this important treatment stage.
ABSTRACT
In this article is demonstrated the practical application of the diagnostic wax-up in the osteointegrated implant oral rehabilitation.
Subject(s)
Dental Implantation, Endosseous , Dental Occlusion , Waxes , Dental Articulators , Dental Impression Technique , Denture, Complete, Upper , Denture, Partial, Fixed , Osseointegration , Patient Care PlanningABSTRACT
It is work out and discuss one of the principal problems in the laser therapy use during the TMJ dysfunction treatment: the determination of the application points for the soft-laser stay, detailing the position of some of them that are essentials to obtain the objectives of this type of treatment.
Subject(s)
Laser Therapy , Temporomandibular Joint Disorders/therapy , Humans , Masticatory Muscles/radiation effects , Neck Muscles/radiation effectsABSTRACT
It is work out and discuss one of the principal problems in the laser therapy use during the TMJ dysfunction treatment: the determination of the application points for the soft-laser stay, detailing the position of some of them that are essentials to obtain the objectives of this type of treatment.
ABSTRACT
It is work out and discuss one of the principal problems in the laser therapy use during the TMJ dysfunction treatment: the determination of the application points for the soft-laser stay, detailing the position of some of them that are essentials to obtain the objectives of this type of treatment.
