ABSTRACT
Four consecutive patients treated for trichotillomania (hair pulling) with clomipramine reported initially dramatic reductions in symptoms. However, three of the four patients had relapsed completely at 3-month follow-up, although all four were still taking previously effective levels of the drug. The fourth patient relapsed for about 2 weeks but regained initial treatment benefits. Implications for the treatment of trichotillomania are discussed.
Subject(s)
Clomipramine/therapeutic use , Trichotillomania/drug therapy , Adolescent , Adult , Female , Follow-Up Studies , Humans , Recurrence , Trichotillomania/psychologySubject(s)
Bipolar Disorder/diagnosis , Schizophrenia/diagnosis , Diagnosis, Differential , Female , Humans , Middle AgedABSTRACT
Six patients with moderate or severe tardive dyskinesia participated in a 14-day double-blind crossover comparison of placebo with 50 g/day of lecithin. There were no side effects, and Abnormal Involuntary Movement Scale (AIMS) ratings of videotaped examinations indicated significant improvement in the dyskinesias of all subjects during the lecithin trial, even with concomitant administration of a constant dose of neuroleptic medication to five patients.
