1.
Bioorg Khim
; 20(6): 669-75, 1994 Jun.
Article
in Russian
| MEDLINE
| ID: mdl-7945461
ABSTRACT
Oligonucleotides with 3'- and 5'-terminal 1-(beta-D-2'-deoxy-threo-pentafuranosyl)thymin residues (inversion at C3'-atom) were obtained by the automatic phosphoramidite synthesis. The modifications protect oligonucleotides from the nuclease degradation and do not affect the stability of nucleic acid duplexes.