[The main directions of public health reforms in the Republic of Uzbekistan].

The article covers the directive documents regulating the development of public health. The main directions of reforms of public health system of the Republic of Uzbekistan are covered too. The statistical data reflecting the structural changes in public health is presented. The purpose and tasks of reformation of the key public health issues in the Republic of Uzbekistan are explained.

[Polypodium hydriforme in the eggs of the sterlet from the northern Dvina river]. / Polypodium hydriforme v ikre severodvinskoi sterliadi.

The paper provides data on the invasion of Acipenser ruthenus (sterlet) in the North Dvina River by Polypodium hydriforme (Cnidaria). Prevalence and intensity of invasion proved to be similar for two fishing sites. Prevalence of invasion exceeded 88%, thus being exceptionally high for P. hydriforme. Intensity of invasion was from 1 to 436 eggs per female. A verage percentage of infected eggs was about 1%.

[Structural characteristics of nematocyst stinging threads from the parasitic cnidarian Polypodium hydriforme]. / Osobennosti stroeniia strekatelnykh nitei nematotsist paraziticheskoi knidarii Polypodium hydriforme.

The structure of discharged nematocyst stinging threads present in free-living individuals of Polypodium hydriforme was studied by scanning and transmission electron microscopy. Not all cnidae of P. hydriforme proved to be atrichous isorhizas (as previously was accepted), but only one of the five nematocyst categories studied. A unique feature of P. hydriforme nematocysts was revealed: their stinging threads possess two strands of spines, rather than 5 or 3, as in Narcomedusae and other Cnidarians, respectively. This fact supplements the evidence in favour of P. hydriforme being a rather isolated branche in the phylogenetic tree of Cnidaria.

[Polar filaments of Myxobolus pseudodispar spores]. / Poliarnye niti spor mikrosporidii Myxobolus pseudodispar.

Spores of Myxobolus pseudodispar from plasmodia occurring in the roach muscles (Rutilus rutilus) were studied by light, transmission and scanning electron microscopy, before and after discharge of their polar filaments. Scanning microscopy reveals that discharged polar filaments bear no spines and their walls are slightly folded. Polar filaments of M. pseudodispar have been compared with stinging threads of the parasitic cnidarium Polypodium hydriforme.

[The ECG in dilated cardiomyopathy with different degrees of the manifestation of cardiosclerosis]. / EKG pri dilatatsionnoi kardiomiopatii s raznoi stepen'iu vyrazhennosti kardioskleroza.

ECG of 46 patients who had died from dilated cardiomyopathy were retrospectively examined in order to evaluate characteristic ECG changes in relation to myocardial sclerotic severity according to autopsy findings. It was found that 1) one of ECG features in this disease is QRS complex morphology in left chest leads in the form of "rS", "RS" as being independent of cardiosclerotic severity. The deep wave S V5-V6 was due not only to rotation shifts during left ventricular hypertrophy (dilatation), which was typical of dilated cardiomyopathy right ventricle mass; 2) as cardiosclerosis progresses, the frequency and severity of intraventricular conduction disturbances progressively increase; 3) ectopic arrhythmias and atrioventricular block are not caused only by cardiosclerosis and likely to be induced by drug therapy (cardiac glycosides); 4) despite cardiosclerotic development in patients with dilated cardiomyopathy, ECG retains voltage criteria of enlarged cardiac cavities; 5) enlarged cardiac cavities can be determined by standard 12 ECG leads in 73.9% of cases.

[The characteristics of cardiosclerosis in dilated cardiomyopathy]. / Kharakteristika kardioskleroza pri dilatatsionnoi kardiomiopatii.

In 52 patients who had died of dilated cardiomyopathy (DCMP) severity of cardiosclerosis (CS) was studied in relation to the patients' age, possible etiological factors, disease duration, and heart weight. In DCMP, diffuse and diffuse small focal CS were common in all segments of the heart, including myocardial portions without macroscopically visible changes. Various types of CS in DCMP were seen in the left ventricular (92.3% cases), ventricular septum (86.5%) and right ventricle (68.2%). There are highly significant variations in the degree of CS in various patients with DC, however, different parts of the heart showed similar changes within the observation. No direct relationship was found between the cardiac weight and severity of CS. Diffuse CS prevailed in cases of DCMP with infective onset of disease. There was a direct relationship between the CS severity and disease duration in DCMP patients.

[Myocarditis and dilated cardiomyopathy (an analysis of questions of etiology, pathogenesis and differential diagnosis in a clinical example)]. / Miokardit i dilatatsionnaia kardiomiopatiia (analiz voprosov étiologii, patogeneza i differentsial'nogo diagnoza na klinichekom primere).

Development and clinical course of dilated cardiomyopathy is analysed in detail on one clinical case. Myocardial biopsy findings, immunologic data and autopsy findings are compared. The data obtained indicate that myocardial lymphocyte infiltration correlates with the rise in titres of antibodies to cytomegalovirus and the virus of herpes simplex as well as increase in serum alpha-interferon, neopterin and beta-2-microglobulin concentrations. Rise in the level of antibodies to cardiolipins is combined with thromboembolic syndrome. The roles of immunological control disturbances and immunity system activation in the pathogenesis of dilated cardiomyopathy as well as possible evolution of myocarditis into dilated cardiomyopathy are discussed.