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1.
Stomatologiia (Mosk) ; 80(4): 17-20, 2001.
Article in Russian | MEDLINE | ID: mdl-11561527

ABSTRACT

Industrial air of copper-melting factory in Almalyk contains a considerable quantity of copper and antioxidant elements (selen and zinc) in combination with poor quantity of prooxidants (ferrum, cobolt, chrome). The workers saliva contains increased concentrations of selen and zinc resultant in lowering intensity of free radical oxidation of lipids in the saliva and subnormal activity of antioxidant system's enzymes. Increased hydroperoxides quantity was discovered in saliva of patients with partial secondary adentia accompanied by hyper activity of antioxidant system's enzymes.


Subject(s)
Air Pollutants, Occupational/metabolism , Antioxidants/metabolism , Copper/metabolism , Saliva/chemistry , Free Radicals , Humans , Jaw, Edentulous/metabolism , Lipid Peroxidation , Metallurgy , Oxidative Stress
2.
Kardiologiia ; 22(3): 76-9, 1982 Mar.
Article in Russian | MEDLINE | ID: mdl-7077908

ABSTRACT

A comprehensive study of the intensity of free radical oxydation of lipids, of changes in the total polyunsaturated free acids and antiradical activity of the blood lipids undertaken in 73 patients with different forms of ischaemic heart disease showed that in all forms of illness there exists intensification of peroxyde oxydation of lipids, more marked in acute myocardial infarction. Rise of antiradical activity of lipids is a sequel to activation of the compensatory mechanisms, directed at neutralization of the negative action of toxic lipid peroxydes. Correlation between the changes in the total polyunsaturated fatty acids and antiradical activity of the lipids permits one to consider that accumulation of polyene acids may be one of the factors helping the intensification of free radical processes.


Subject(s)
Coronary Disease/blood , Fatty Acids/blood , Lipids/blood , Adult , Angina Pectoris/blood , Free Radicals , Humans , Lipid Peroxides/blood , Male , Middle Aged , Myocardial Infarction/blood , Oxidation-Reduction
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