ABSTRACT
PURPOSE: Evaluate therapeutic results of transcatheter segmental hepatic artery chemo-oily-embolization (segmental TAE) against advanced hepatocellular carcinomas (HCC) accompanied by portal tumor thrombus (PTT). METHODS: Segmental TAE was performed in nine patients with hepatic cirrhosis and advanced HCCs accompanied by PTT. Four subsegmental portal branches were obstructed by PTT in three patients, and two were obstructed in the remaining six patients. TAE was performed into the targeted segmental hepatic artery followed by embolization with gelatin sponge particles. RESULTS: In one patient undergoing subsequent resection, a marked anticancer effect on the PTT was demonstrated histologically. In the eight other patients who did not undergo subsequent resection, the cumulative survival rates were 67% at 6 months, 44% at 1 year, and 22% at 2 years. No serious complications were noted. CONCLUSIONS: This therapeutic approach is thought to be a useful treatment for HCC with PTT, because it reinforces anticancer effects and can be performed more safely than conventional transcatheter arterial embolization.
Subject(s)
Carcinoma, Hepatocellular/therapy , Chemoembolization, Therapeutic/methods , Liver Neoplasms/therapy , Neoplastic Cells, Circulating/pathology , Portal Vein , Vascular Neoplasms/therapy , Aged , Antibiotics, Antineoplastic/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Carcinoma, Hepatocellular/pathology , Carcinoma, Hepatocellular/surgery , Combined Modality Therapy , Epirubicin/administration & dosage , Female , Follow-Up Studies , Gelatin/administration & dosage , Hepatectomy , Hepatic Artery , Humans , Injections, Intralesional , Iodized Oil/administration & dosage , Liver Neoplasms/pathology , Liver Neoplasms/surgery , Male , Middle Aged , Mitomycin/administration & dosage , Portal Vein/pathology , Remission Induction , Survival Rate , Vascular Neoplasms/pathologyABSTRACT
We have experienced three adult intussusception cases with colorectal cancer. In all three cases CT studies were performed prior to administering a barium enema, where we could make the exact diagnosis of the lesions in both the plain and the contrast studies. In the CT studies, the intussusception lesions showed the characteristic eccentric layered pattern. It was difficult to distinguish the tumors from the edematous intestinal walls at the proceeding portion in two cases. While in one case, the proceeding portion (the tumor itself) was pointed out as the enhanced soft tissue density mass of layered pattern with the irregular margins.
Subject(s)
Colorectal Neoplasms/diagnostic imaging , Intussusception/diagnostic imaging , Tomography, X-Ray Computed , Aged , Colorectal Neoplasms/complications , Female , Humans , Intussusception/complications , Male , Middle AgedABSTRACT
An investigation was conducted into the adverse reactions, especially delayed reactions, of non-ionic contrast media. Out of a total number of 3,411 people treated, there were 45 cases (1.32%) in which adverse reactions were observed, and of these 45 cases, 14 cases (0.41% of the total number) showed delayed adverse reactions. Of the aforesaid 14 patients with delayed adverse reactions, all of them developed skin eruptions, but no seriously adverse effects were eventually observed.
