ABSTRACT
Ischemic colitis is a well-recognized complication occurring in renal transplant recipients. It has often been associated with cytomegalovirus (CMV) vasculitis. However, the diagnosis of this pathology in the absence of CMV suggests that other etiological factors might be involved. Drugs inducing mesenteric vasoconstriction, such as non-steroidal anti-inflamatory drugs (NSAIDs) and cyclosporine could be related to this entity.
Subject(s)
Colitis, Ischemic/etiology , Colon/pathology , Kidney Transplantation/adverse effects , Colitis, Ischemic/pathology , Colitis, Ischemic/therapy , Female , Humans , Immunosuppressive Agents/therapeutic use , Kidney Transplantation/methods , Middle Aged , Postoperative ComplicationsABSTRACT
La colitis isquémica es una complicación reconocida en receptores de trasplante renal, que casi siempre se asocia a vasculitis por citomegalovirus (CMV). Sin embargo, el diagnóstico de esta patología en ausencia de CMV sugiere que otros factores etiológicos pueden estar involucrados en su patogenia. Las drogas que inducen vasoconstricción mesentérica, como los anti-inflamatorios no esteroides (AINEs) y la ciclosporina, podrían relacionarse con esta entidad
Ischemic colitis is a well-recognized complication occurring in renal transplant recipients. It has ofter been associated with cytomegalovirus (CMV) vasculitis. However, the diagnosis of this pathology in the absence of CMV suggests that other etiological factors might be involved. Drugs inducing mesenteric vasoconstriction, such as non-steroidal anti-inflamatory drugs (NSAIDs) and cyclosporine could be related to this entity
Subject(s)
Female , Middle Aged , Humans , Colitis, Ischemic/etiology , Colon/pathology , Kidney Transplantation/adverse effects , Postoperative Complications , Colitis, Ischemic/pathology , Colitis, Ischemic/therapy , Immunosuppressive Agents/therapeutic use , Kidney Transplantation/methods , Cyclosporine/therapeutic use , VasoconstrictionABSTRACT
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.
Subject(s)
Humans , Male , Adult , Kidney Transplantation , Porphyria Cutanea Tarda/etiology , Renal Dialysis/adverse effects , Hydroxychloroquine , Porphyria Cutanea Tarda/diagnosis , Porphyria Cutanea Tarda/drug therapy , Time FactorsABSTRACT
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.(Au)
Subject(s)
Humans , Male , Adult , Kidney Transplantation , Porphyria Cutanea Tarda/etiology , Hydroxychloroquine/therapeutic use , Porphyria Cutanea Tarda/diagnosis , Porphyria Cutanea Tarda/drug therapy , Renal Dialysis/adverse effects , Time FactorsABSTRACT
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.
Subject(s)
Kidney Transplantation , Porphyria Cutanea Tarda/etiology , Adult , Humans , Hydroxychloroquine/therapeutic use , Male , Porphyria Cutanea Tarda/diagnosis , Porphyria Cutanea Tarda/drug therapy , Renal Dialysis/adverse effects , Time FactorsABSTRACT
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.
