Nutritional status and constipation scoring of inguinal hernia patients: a case-control study.

PURPOSE: There are many risk factors for inguinal hernia that have been determined in the literature, but the relationship between nutritional status and inguinal hernia has not yet been examined. In this study, we evaluated the constipation scale and food consumption of patients with inguinal hernia. METHODS: This prospective case-control study was performed between March 2018 and March 2019. The patients who were admitted for inguinal hernia operation were the case group, and those patients who had been admitted to the same hospital without inguinal hernia were the control group. The age, body mass index, alcohol and smoking habits, daily activity, and the Wexner constipation scoring were examined using a questionnaire and 3-day food consumption records were noted. RESULTS: A total of 203 volunteers were included in the study. Of these, 88 patients were in the control group, and 115 patients were in the case group. The age and gender distribution of the groups was similar. Cigarette and alcohol usages are statistically high in the case group. The Wexner constipation scale of the groups was statistically high in the case group. In the univariate analysis, smoking, alcohol consumption, total constipation score, red meat consumption, chicken consumption, bread consumption, low fiber consumption, low egg consumption, low carbohydrate, and low energy intake were effective in hernia formation, and in the multivariate analysis, total constipation score, red meat consumption, chicken consumption, excess bread consumption, low energy intake, and low fiber consumption were significant as independent variables. CONCLUSION: Our study is the first to evaluate whether there is a relationship between inguinal hernia and nutrition, according to the literature. Lifestyle modifications and a healthy diet with the consumption of less meat and more vegetables may have an impact on the reduction of hernia occurrence.

EFFECTIVENESS OF ANETHUM GRAVEOLENS L. ON ANTIOXIDANT STATUS, THYROID FUNCTION AND HISTOPATHOLOGY.

CONTEXT: Anethum graveolens L. is used in the treatment of numerous diseases. But there is limited data about the Anethum graveolens efficiency in thyroid tissue. OBJECTIVE: The aim of this study is to assess the functional and histopathological changes in thyroid tissues from rats treated with Anethum graveolens L. extract. DESIGN: This is an experimental animal study and duration of the study was 30 days. SUBJECTS AND METHODS: Twenty-eight female Wistar Albino rats were divided into four equal groups. A gavage of Anethum graveolens L. extract at 0, 50, 150 and 300 mg/kg/day doses were given to the rats with 1 mL 0.9% NaCl, respectively, for 30 days. Blood was taken at day 0, 15 and 30. fT3, fT4, TSH values and antioxidant efficiency were observed. Also the thyroidectomy tissue was assessed histopathologically. RESULTS: There is no difference observed in the fT3, fT4 and TSH values of groups 1, 2 and 3 at day 1, 15 and 30 (p>0.05); however, in group 4, TSH value decreased on days 15 and 30 when compared to day 1 and the other groups (p<0.05). Also the hypertrophy and thyroid follicular cell hyperplasia were significantly increased in group 4 (p<0.05). There is no difference in antioxidant efficiency in any of the groups (p>0.05). CONCLUSION: Anethum graveolens L. extract is effective on both the function and the histology of thyroid tissue but it has no effect on antioxidant status.