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1.
Biomicrofluidics ; 10(1): 011902, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26858808

ABSTRACT

Superparamagnetic micro-bead chains and microswimmers under the influence of an oscillating magnetic field are studied experimentally and numerically. The numerical scheme composed of the lattice Boltzmann method, immersed boundary method, and discrete particle method based on the simplified Stokesian dynamics is applied to thoroughly understand the interaction between the micro-bead chain (or swimmer), the oscillating magnetic field, and the hydrodynamics drag. The systematic experiments and simulations demonstrated the behaviors of the microchains and microswimmers as well as the propulsive efficiencies of the swimmers. The effects of key parameters, such as field strengths, frequency, and the lengths of swimmer, are thoroughly analyzed. The numerical results are compared with the experiments and show good qualitative agreements. Our results proposed an efficient method to predict the motions of the reversible magnetic microdevices which may have extremely valuable applications in biotechnology.

2.
Brain Cogn ; 61(3): 280-5, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16581168

ABSTRACT

The functional link between the amygdala and hippocampus in humans has not been well documented. We examined the effect of unpleasant loud noise on hippocampal and amygdaloid activities during picture encoding by means of fMRI, and on the correct response in humans. The noise reduced activity in the hippocampus during picture encoding, decreased the correct response and increased the activity of the amygdala. A path diagram using structural equation modeling suggested that hippocampus activity might be depressed by high amygdala activity. Therefore, noise should diminish memory by reducing hippocampal activity, which might be depressed by high amygdala activity.


Subject(s)
Hippocampus/physiopathology , Magnetic Resonance Imaging , Noise/adverse effects , Visual Perception/physiology , Adult , Amygdala/physiopathology , Female , Humans , Male , Memory Disorders/diagnosis , Memory Disorders/etiology , Memory Disorders/physiopathology , Nerve Net/physiopathology , Prefrontal Cortex/physiopathology
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