1.
J Pediatr Hematol Oncol
; 34(4): e134-6, 2012 May.
Article
in English
| MEDLINE
| ID: mdl-22430585
ABSTRACT
Most invasive fungal sinusitis occurs in immunocompromised adult patients. We present the case study of a 12-year-old boy diagnosed with acute myeloblastic leukemia undergoing chemotherapy. He developed a progressive darkening discoloration over the dorsum of the nose that turned into an eschar. Nasal endoscopy revealed extensive necrotic tissue in the nasal cavity mucosa, inferior and middle turbinates, and septal cartilage that extended to the eschar of the skin over the nasal dorsum. Histopathology showed aspergillus invasive fungal rhinosinusitis.
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/adverse effects , Aspergillosis , Immunocompromised Host , Leukemia, Myeloid, Acute/drug therapy , Rhinitis , Sinusitis , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Aspergillosis/chemically induced , Aspergillosis/microbiology , Aspergillosis/pathology , Child , Fatal Outcome , Humans , Leukemia, Myeloid, Acute/immunology , Leukemia, Myeloid, Acute/microbiology , Leukemia, Myeloid, Acute/pathology , Male , Nasal Cavity/microbiology , Nasal Cavity/pathology , Rhinitis/chemically induced , Rhinitis/microbiology , Rhinitis/pathology , Sinusitis/chemically induced , Sinusitis/microbiology , Sinusitis/pathology
2.
J Paediatr Child Health
; 46(12): 779, 789, 2010 Dec.
Article
in English
| MEDLINE
| ID: mdl-21166919
