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Angew Chem Int Ed Engl
; 51(34): 8516-9, 2012 Aug 20.
Article
in English
| MEDLINE
| ID: mdl-22807275
ABSTRACT
Superelectrophiles: Formamides were designed that when treated with triflic anhydride would be transformed into superelectrophilic amidine dications. These dications were so electrophilic that they underwent in situ dealkylation by the triflate anion (see scheme; Tf = trifluoromethanesulfonyl). DFT calculations were used to determine the mechanistic details of the dealkylation reaction.