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1.
Surg Infect (Larchmt) ; 11(5): 463-7, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20583955

ABSTRACT

BACKGROUND: Necrotizing fasciitis is a serious infection that originates in the subcutaneous tissues. Although many reports have been published about necrotizing infections of other anatomical sites, retroperitoneal necrotizing soft tissue infection is a rare entity that has been described in only a few case reports. The etiology and clinical course of retroperitoneal necrotizing fasciitis can be variable and it is often difficult to identify the etiology of the infective process. CASE REPORT: We report a 58-year-old man with rapidly progressive, gas-producing, necrotizing inflammation in the retroperitoneum, complicated with genital involvement resembling Fournier gangrene. The patient was managed successfully by aggressive drainage, debridement, and sequential laparotomies to track and control the extensive necrosis of the retroperitoneum and perineum, in addition to systemic care to control sepsis. After his general condition stabilized, early rectosigmoid adenocarcinoma was identified and resected curatively. He remained well at follow up, six months after discharge. RESULTS: In retrospect, the trigger of the disease process was unclear. Although it was believed possibly to be due to the colon lesion, adenocarcinoma of the rectosigmoid colon was identified and the patient was managed successfully. CONCLUSIONS: Similar to necrotizing infections at other anatomical sites, early diagnosis and timely surgical intervention and systemic antimicrobial therapy are mandatory for treating patients with retroperitoneal necrotizing fasciitis.


Subject(s)
Fasciitis, Necrotizing/complications , Fasciitis, Necrotizing/diagnosis , Fournier Gangrene/diagnosis , Genital Diseases, Male/diagnosis , Retroperitoneal Space/pathology , Adenocarcinoma/diagnosis , Adenocarcinoma/surgery , Anti-Bacterial Agents/therapeutic use , Debridement , Drainage , Fasciitis, Necrotizing/pathology , Fasciitis, Necrotizing/therapy , Fournier Gangrene/pathology , Genital Diseases, Male/pathology , Genital Diseases, Male/therapy , Humans , Laparotomy , Male , Middle Aged , Radiography, Abdominal , Rectal Neoplasms/diagnosis , Rectal Neoplasms/surgery , Tomography, X-Ray Computed
2.
Childs Nerv Syst ; 21(3): 234-6, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15290193

ABSTRACT

CASE REPORT: A 7-year-old boy was involved in a road traffic accident. A computed tomography scan revealed an acute subdural hematoma (ASDH) of the posterior fossa, traumatic subarachnoid hemorrhage, and distortion of the brain stem. Removal of the ASDH was completed 3.5 h after injury. After extubation, the patient rapidly recovered consciousness. He was able to follow commands, although he did not speak. He began to utter 14 days after the injury. His speech became normal 39 days after injury. A magnetic resonance imaging scan revealed a post-contusional change in the right cerebellum and an ischemic lesion in the pons. DISCUSSION: Immediate removal of the hematoma is the only therapy for patients with ASDH of the posterior fossa. Although any lesions of the dentate nucleus, red nucleus, thalamus, cerebral cortex, and pons, all of which are involved in this case, are able to cause mutism, his mutism was primarily caused by the severe ASDH of the posterior fossa. The transient nature of this syndrome suggests that the cause of the mutism is trauma-related edema and/or transient ischemia of these structures.


Subject(s)
Mutism/etiology , Neurosurgical Procedures/adverse effects , Postoperative Complications/etiology , Accidents, Traffic , Child , Cranial Fossa, Posterior/pathology , Cranial Fossa, Posterior/surgery , Hematoma, Subdural, Acute/pathology , Hematoma, Subdural, Acute/surgery , Humans , Male , Tomography, X-Ray Computed/methods
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