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1.
Urol Pract ; 6(3): 180-184, 2019 May.
Article in English | MEDLINE | ID: mdl-37300097

ABSTRACT

INTRODUCTION: We assessed the face, content and construct validity of a newly created vasectomy simulation module. METHODS: Pre-simulation and post-simulation surveys quantifying simulation effectiveness, impact on confidence level and critiques of the overall design were obtained in July 2015 to assess face and content validity. Residents were subdivided based on year of residency and construct validity was ascertained via a 20-objective checklist and individual Likert score as graded by a single attending physician in a blinded fashion. RESULTS: Two medical students and 8 residents (2 Pre-Urology, 2 Uro-1, 2 Uro-2 and 2 Uro-3) were included in the analysis. The response rate was 100% (10 of 10) for the simulation exercise and all residents (100%, 8 of 8) were used in the metric data analysis. Simulation increased the confidence to perform a vasectomy independently on average 1.58 points based on pre-simulation and post-simulation questionnaire analysis (95% CI 1.09-2.89, p=0.02). Training year had a significantly positive association (overall p <0.01) with number of objectives completed. CONCLUSIONS: Our enhanced vasectomy simulation module demonstrated excellent face, content and construct validity.

2.
Can J Urol ; 24(3): 8795-8801, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28646934

ABSTRACT

INTRODUCTION: To compare visual analog scale (VAS) pain scores between patients with a 2-minute versus 10-minute delay of peri-prostatic lidocaine injection prior to transrectal ultrasound-guided prostate biopsies (TRUS-bx). MATERIALS AND METHODS: Eighty patients who underwent standard 12-core TRUS-bx by a single surgeon were prospectively randomized into four different treatment arms: bibasilar injection with a 2-minute delay, bibasilar injection plus a single apical injection with a 2-minute delay, bibasilar injection with a 10-minute delay, and bibasilar injection plus a single apical injection with a 10-minute delay. Patients were asked to report their level of pain on the VAS (0-10, with 10 indicating unbearable pain) at the following intervals: probe insertion (baseline), after each core, and post-procedure. The primary outcome measure was mean VAS score across all 12 cores minus baseline VAS score, which we refer to baseline-adjusted mean VAS score. RESULTS: Baseline-adjusted mean VAS score was significantly higher for the 2-minute delay group compared to the 10-minute delay group (mean: -0.7 versus -1.6, p = 0.025). Subset analysis of biopsies 1-3, 4-6, 7-9 and 10-12 also demonstrated higher baseline-adjusted mean VAS scores in the 2-minute delay group (all p ≤ 0.043). CONCLUSIONS: Lower TRUS-bx VAS scores can be achieved by extending the time from lidocaine injection to onset of prostate biopsy from 2 to 10 minutes.


Subject(s)
Anesthesia, Local , Anesthetics, Local , Endoscopic Ultrasound-Guided Fine Needle Aspiration/adverse effects , Lidocaine , Pain, Procedural/prevention & control , Prostate/pathology , Adult , Aged , Aged, 80 and over , Anesthetics, Local/administration & dosage , Humans , Lidocaine/administration & dosage , Male , Middle Aged , Pain Measurement , Prospective Studies , Time Factors
3.
Urology ; 99: 186-191, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27771424

ABSTRACT

OBJECTIVE: To compare the frequency of postoperative encounters in the 30-day and 90-day postoperative periods for various bladder outlet obstruction surgical therapies. MATERIALS AND METHODS: All patients who underwent transurethral resection of the prostate (TURP), GreenLight laser photovaporization of the prostate (GL-PVP) (American Medical Systems Inc.), and holmium laser enucleation of the prostate (HoLEP) from January 1, 2012 to December 31, 2014 were followed for 6 months postoperatively. All postoperative encounters such as patient calls or questions, catheter exchanges or removals, and hospital-based readmissions or emergency department visits were recorded in the electronic medical record. RESULTS: Two hundred and ninety-one consecutive patients underwent outlet procedures during the study period: TURP (N = 199; mean age, 71 years; mean body mass index [BMI], 28.5), HoLEP (N = 60; mean age, 68 years; mean BMI, 28.1), or GL-PVP (N = 32; mean age, 72 years; mean BMI, 29.3). No statistically significant difference was observed for age, BMI, preoperative American Urological Association symptom score, or preoperative maximum flow velocity between the 3 groups. Thirty-day postoperative encounters differed significantly between the 3 surgery types (P < .001). Specifically, there were fewer encounters within 30 days of surgery for TURP compared to both HoLEP (≥1 encounter: TURP = 48.7%, HoLEP = 66.7%; P = .006) and GL-PVP (≥1 encounter: TURP = 48.7%, GL-PVP = 93.7%; P < .001). The number of encounters within 90 days postoperatively was also significantly lower for TURP patients (P < .001). CONCLUSION: TURP results in fewer postoperative encounters in both the 30-day and 90-day postoperative periods compared to HoLEP and GL-PVP. Laser prostate therapies may place increased burden on clinic staff during the 30-day and 90-day postoperative periods.


Subject(s)
Minimally Invasive Surgical Procedures/adverse effects , Office Visits/trends , Postoperative Complications/epidemiology , Prostatic Hyperplasia/surgery , Risk Assessment/methods , Transurethral Resection of Prostate/adverse effects , Urinary Bladder Neck Obstruction/etiology , Aged , Aged, 80 and over , Follow-Up Studies , Humans , Incidence , Laser Therapy/adverse effects , Laser Therapy/methods , Male , Middle Aged , Minimally Invasive Surgical Procedures/methods , Prognosis , Prostatic Hyperplasia/complications , Retrospective Studies , Time Factors , Transurethral Resection of Prostate/methods , Treatment Outcome , United States/epidemiology , Urinary Bladder Neck Obstruction/surgery
4.
J Laparoendosc Adv Surg Tech A ; 25(12): 966-70, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26583763

ABSTRACT

PURPOSE: A prophylactic ureteral localization stent (PULSe) placed by urologists aids in intraoperative localization and detection of suspected ureteral injury during complex colorectal surgery (CRS) cases. We evaluated the incidence and management of urologic-induced complications secondary to PULSe placement during CRS cases at a single center. MATERIALS AND METHODS: We performed a retrospective review of all patients who underwent cystoscopy and PULSe placement at the time of CRS over a 12-month period. Bilateral 5 French ×70-cm TigerTail® (Bard Medical Division, Covington, GA) PULSe devices were placed without assistance of routine fluoroscopy. RESULTS: Ninety-nine patients (mean age, 58.1 years; range, 17-88 years) underwent bilateral PULSe placement, with a male:female ratio of 44:55 and a mean body mass index of 26.8 (17.0-38.6) kg/m(2). Mean pre- and postprocedural creatinine levels were 0.91 and 1.01 mg/dL, respectively. Twenty-two of 99 (22%) cases utilized a guidewire to aid in placement of PULSe. Four Clavien grade IIIb complications occurred: mucosal edema, reflex anuria, ureteral perforation, and ureteral obstruction secondary to significant clot burden. Three of the grade IIIb complications were managed endoscopically with double-J stent placement. The ureteral perforation case required percutaneous nephrostomy tube placement. Subgroup analysis of the four grade IIIb complications revealed a mean age of 62.3 years, body mass index of 26.98 kg/m(2), and pre- and postprocedural creatinine levels of 0.95 and 4.83 mg/dL, respectively. Only one of the four grade IIIb complications utilized a guidewire prior to PULSe placement. CONCLUSIONS: The incidence of Clavien grade III urologic-induced complications during PULSe placement is approximately 2% (4/188). Mandatory adoption of fluoroscopy and guidewires may be required to minimize complications of PULSe placement.


Subject(s)
Colorectal Surgery , Cystoscopy/adverse effects , Intraoperative Complications/etiology , Stents/adverse effects , Ureter/injuries , Ureteral Obstruction/etiology , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Incidence , Intraoperative Complications/epidemiology , Intraoperative Complications/therapy , Male , Middle Aged , Retrospective Studies , Ureteral Obstruction/epidemiology , Ureteral Obstruction/therapy , Young Adult
5.
J Endourol ; 27(2): 230-7, 2013 Feb.
Article in English | MEDLINE | ID: mdl-22849341

ABSTRACT

PURPOSE: We designed a three-phase bedside assistant training course for those involved with robot-assisted radical prostatectomy (RARP). We also examined whether an experienced RARP team (>1000 cases) would perceive benefit from this three-phase bedside assistant training course. MATERIALS AND METHODS: The 13 RARP bedside assistants were identified at our institution (three surgical technicians, two surgical assistants, four resident trainees, and four physician assistants). The course consisted of three phases that were taught at three separate morning sessions. Phase 1 focused on robot functionality. Phase 2 consisted of a step-by-step video session that focused on the assistant's role in each RARP step. Phase 3 involved three hands-on laparoscopic drills that were to be completed in a predetermined period. Pre- and postcourse questionnaires assessed learner knowledge pertaining to RARP. RESULTS: All 13 learners completed the three-phase training course. Nine of 13 learners thought this course would be beneficial, although, 9 of 13 already thought that they were good RARP assistants before the course. Ten of 13 learners were able to complete the hands-on drills in the predetermined periods. On completion of the course, every learner thought the course was beneficial and that it should be repeated annually. Twelve of 13 thought that the course made them a better assistant and that their intra-abdominal spatial orientation was greatly improved. Seven of the learners thought the hands-on drills were the most beneficial portion of the course, while the other six found the step-by-step lecture the most beneficial. CONCLUSIONS: A three-phase hands-on RARP bedside assistant training course is beneficial to and desired by an experienced RARP team at least annually.


Subject(s)
Clinical Competence , Computer Simulation , Physician Assistants/education , Prostatectomy/education , Robotics/education , Curriculum , Humans , Male , Surveys and Questionnaires
6.
Int Braz J Urol ; 38(5): 704-6, 2012.
Article in English | MEDLINE | ID: mdl-23131513

ABSTRACT

Inferior Vena Cava (IVC) filters are mechanical devices implanted to provide prophylaxis against pulmonary emboli in patients for whom standard anticoagulation is either inadequate or contraindicated. A 67-year-old female with a 10-year-old indwelling IVC filter underwent robotic assisted laparoscopic partial nephrectomy for a right upper pole renal mass. Renal hilum dissection was complicated by adhesions secondary to eroded IVC filter struts. IVC filter erosion is a well-described phoenomena in both the radiologic and surgical literature. As many as 25% of filters are noted to be radiographically eroded; however, the incidence of clinically significant erosion is much less. Given the placement of endovascularly delivered IVC filters in close proximity to many urologic operative fields, it is important for urologists to be aware of the potential of eroded devices when pursuing para-caval dissections.


Subject(s)
Laparoscopy/methods , Nephrectomy/methods , Surgery, Computer-Assisted/methods , Vena Cava Filters , Vena Cava, Inferior/diagnostic imaging , Aged , Female , Humans , Tomography, X-Ray Computed
7.
Int. braz. j. urol ; 38(5): 704-706, Sept.-Oct. 2012. ilus
Article in English | LILACS | ID: lil-656000

ABSTRACT

Inferior Vena Cava (IVC) filters are mechanical devices implanted to provide prophylaxis against pulmonary emboli in patients for whom standard anticoagulation is either inadequate or contraindicated. A 67-year-old female with a 10-year-old indwelling IVC filter underwent robotic assisted laparoscopic partial nephrectomy for a right upper pole renal mass. Renal hilum dissection was complicated by adhesions secondary to eroded IVC filter struts. IVC filter erosion is a well-described phoenomena in both the radiologic and surgical literature. As many as 25% of filters are noted to be radiographically eroded; however, the incidence of clinically significant erosion is much less. Given the placement of endovascularly delivered IVC filters in close proximity to many urologic operative fields, it is important for urologists to be aware of the potential of eroded devices when pursuing para-caval dissections.


Subject(s)
Aged , Female , Humans , Laparoscopy/methods , Nephrectomy/methods , Surgery, Computer-Assisted/methods , Vena Cava Filters , Vena Cava, Inferior , Tomography, X-Ray Computed
8.
J Laparoendosc Adv Surg Tech A ; 21(4): 349-51, 2011 May.
Article in English | MEDLINE | ID: mdl-21486152

ABSTRACT

Ureteral obstruction secondary to retrocaval ureter is rarely reported in the urologic literature. Symptomatic retrocaval ureters usually present in the 3rd and 4th decade of life. Standard treatment involves ureteroureterostomy approximating the ureter anterior to the vena cava. We describe the initial presentation, imaging, port placement, and operative technique including video presentation of a robot-assisted laparoscopic repair of a retrocaval ureter.


Subject(s)
Laparoscopy/methods , Robotics , Ureter/abnormalities , Ureter/surgery , Ureteral Obstruction/etiology , Ureteral Obstruction/surgery , Humans , Male , Middle Aged , Urologic Surgical Procedures/methods
9.
J Laparoendosc Adv Surg Tech A ; 21(2): 153-6, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21284516

ABSTRACT

OBJECTIVES: The Habib 4 × radiofrequency-assisted bipolar hemostatic device (AngioDynamics) was used during select open partial nephrectomies to minimize blood loss and prevent warm renal ischemia. The article and video demonstrate this novel technique for partial nephrectomies in select renal masses. METHODS: Patients with large renal tumors requiring partial nephrectomy where avoidance of warm ischemia was deemed imperative underwent open partial nephrectomy at our institution utilizing the Habib 4 × radiofrequency ablation device to avoid prolonged warm ischemia time and prevent blood loss. RESULTS: We have used the device successfully in 4 partial nephrectomies (2 patients with solitary kidneys, 2 patients with bilateral large masses). The mean age was 65 years. Mean tumor size was 6.4 cm. All tumors were located either in the upper pole or lower pole of the kidney. Mean hospital stay was 4.6 days. No patient received an intraoperative blood transfusion. Two patients required long-term ureteral stenting and surgical drainage for urine leakage. CONCLUSIONS: Bipolar radiofrequency ablation offers avoidance of hilar clamping in carefully selected large partial nehrectomies.


Subject(s)
Catheter Ablation/instrumentation , Hemostasis, Surgical/instrumentation , Kidney Neoplasms/surgery , Nephrectomy/instrumentation , Aged , Cohort Studies , Equipment Design , Female , Humans , Kidney Neoplasms/complications , Kidney Neoplasms/pathology , Male , Middle Aged , Nephrectomy/methods , Patient Selection , Retrospective Studies , Treatment Outcome , Warm Ischemia
10.
Urology ; 77(5): 1238-42, 2011 May.
Article in English | MEDLINE | ID: mdl-21256564

ABSTRACT

INTRODUCTION: The da Vinci Surgical System has become extremely popular in the field of urology for procedures requiring complex reconstructive maneuvers, such as radical prostatectomy and pyeloplasty. A natural extension of these procedures is the use of the da Vinci system for complex urinary tract reconstruction deep in the pelvis, such as bladder diverticulectomy. TECHNICAL CONSIDERATIONS: In our report and accompanying Video, we have demonstrated some technical tips and tricks with regard to patient selection, preoperative imaging, patient positioning, port placement, intraoperative diverticulum recognition/excision, and cystotomy repair that the surgeon might find beneficial for successful completion of robotic-assisted bladder diverticulectomy. CONCLUSIONS: The tips and tricks we have presented might aid in the successful completion of robotic bladder diverticulectomy.


Subject(s)
Diverticulum/surgery , Robotics , Urinary Bladder Diseases/surgery , Humans , Urologic Surgical Procedures/methods
11.
Urology ; 77(6): 1288-91, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21215433

ABSTRACT

OBJECTIVES: To complete a prospective evaluation of serum amylase and lipase levels before and after shock wave lithotripsy (SWL) for renal stones. We also compared these serum levels to those of patients undergoing percutaneous and ureteroscopic stone surgery. SWL injury to the pancreas should be noted by an increase in serum amylase and lipase. METHODS: A prospective evaluation of 38 patients (16 who underwent SWL, 15 who underwent percutaneous nephrostolithotomy, and 7 who underwent ureteroscopic stone manipulation) who underwent treatment of renal calculi at our institution was completed. The control group was the combined group of patients who had undergone percutaneous nephrostolithotomy or ureteroscopic stone manipulation. The serum amylase and lipase levels were measured before the procedure, immediately after the procedure (2 hours), and ≥30 days after the procedure. RESULTS: No statistically significant difference was found in the change from before to immediately after the procedure between the SWL group and the controls in amylase (median decrease 6 U/L vs 11 U/L, P = .45) or lipase (median decrease 4 U/L vs 9 U/L, P = .31). Also, no statistically significant evidence was seen in the change from before to >30 days after the procedure between the SWL group and controls in the amylase level (median increase 0 U/L vs 2 U/L, P = 1.00) or lipase (median change 2 U/L increase vs 1 U/L decrease, P = .96). CONCLUSIONS: SWL does not appear to noticeably increase the serum amylase and lipase level directly postoperatively or >30 days after the procedure compared with baseline or compared with the controls.


Subject(s)
Kidney Calculi/complications , Kidney Calculi/therapy , Lithotripsy/adverse effects , Nephrostomy, Percutaneous/adverse effects , Pancreas/pathology , Ureteroscopy/adverse effects , Adult , Aged , Aged, 80 and over , Amylases/blood , Female , Humans , Lipase/blood , Male , Middle Aged , Pancreas/injuries , Prospective Studies , Time Factors , Treatment Outcome
12.
J Endourol ; 24(10): 1665-9, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20849279

ABSTRACT

PURPOSE: To analyze and compare the safety and peri-operative outcomes of fellowship-trained robotic surgeons (FEL) and experienced open surgeons (OE) incorporating robot-assisted laparoscopic prostatectomy (RALP) into practice. MATERIALS AND METHODS: Multiinstitutional, prospective data were collected on the first 30 RALP performed by FEL and OE (defined as over 1000 prostatectomies) incorporating RALP into practice. Morbidity from the peri-operative course was evaluated as were operative outcomes. The second 30 cases from the OE group were evaluated to assess for improvement with experience. RESULTS: There were no rectal injuries or death in either group. Blood transfusion rates did not differ between the two groups (2% vs. 3%, p = 0.65). Open conversion occurred three times in the OE group but only within the first 30 cases. In the first 30 cases FEL had statistically lower rates of positive margins (15% vs. 34%, p = 0.008) and decreased likelihood of prolonged urethral catheter leakage (5% vs. 19%, p = 0.009). The FEL group had lower rates of failure of prostate-specific antigen to nadir < 0.15 ng/mL (2% vs. 10%, p = 0.056). There were no reoperations in the FEL group but present in 2% of the OE group initially. The second 30 cases of the OE group noted a statistical improvement for all parameters with margin rates and the requirement of prolonged catheterization becoming statistically comparable to those of the FEL group. CONCLUSIONS: OE can safely incorporate RALP into practice and achieve outcomes comparable to FEL quickly. As anticipated, FEL achieve these endpoints earlier in their practice.


Subject(s)
Clinical Competence , Laparoscopy/education , Learning Curve , Prostatectomy/education , Prostatectomy/methods , Robotics/education , Aged , Fellowships and Scholarships , Humans , Male , Middle Aged , Prospective Studies , Safety , Treatment Outcome
13.
Urology ; 76(2): 488-93, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20034657

ABSTRACT

OBJECTIVES: To examine whether simple tips and tricks provided in this manuscript and video make robotic reconstruction of the urinary tract possible from the renal calyx to the bladder. The da Vinci Surgical System (Intuitive Surgical, Inc., Sunnyvale, CA) has been widely accepted by urologists for complex reconstructive maneuvers such as radical prostatectomy and pyeloplasty. METHODS: The manuscript and accompanying video outline tips and tricks for patient selection, patient evaluation, port placement, dissection techniques, robotic docking, ureteral repair, and stent management for complex urinary tract reconstruction of the upper urinary tract from the level of the renal calyx to the bladder. RESULTS: Modifications such as port placement, robotic docking techniques, and ureter reconstruction have simplified the technique of complex robotic-assisted laparoscopic reconstruction of the urinary tract. CONCLUSIONS: Numerous scenarios can be encountered during robotic-assisted laparoscopic repair of the upper urinary tract. Simple tips and tricks provided in this manuscript and video make robotic reconstruction of the urinary tract possible from the renal calyx to the bladder.


Subject(s)
Kidney Calices/surgery , Laparoscopy/methods , Robotics , Ureter/surgery , Ureteral Obstruction/surgery , Urinary Bladder/surgery , Humans , Urologic Surgical Procedures/methods
14.
Radiother Oncol ; 93(2): 203-6, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19766337

ABSTRACT

PURPOSE: To evaluate late toxicity in patients who received salvage external beam radiotherapy (EBRT) for a detectable prostate-specific antigen (PSA) level after radical prostatectomy (RP). METHODS: A cohort of 308 consecutive patients underwent salvage EBRT from July 1987 through June 2003 for a detectable PSA level after RP. All were treated with high-energy photons (6-20 MV) to a median dose of 64.8 Gy (range: 54.0-72.4 Gy) in 1.8- to 2.0-Gy fractions. RESULTS: Median follow-up from the completion of EBRT was 60 months (range: 1 day-174 months). Late toxicity occurring more than 90 days after EBRT completion was identified in 41 patients (13%). Twelve patients (3.9%) had grade 2 urethral strictures and were treated with urethral dilation, 3 patients had grade 3 cystitis, and 1 had a grade 4 rectal complication. These numbers correspond to an estimated 0.7% (95% confidence interval, 0.0-1.6%) of patients experiencing a grade 3 or 4 complication by 5 years after the start of EBRT. CONCLUSIONS: Salvage EBRT for a detectable PSA level after RP is the only curative treatment in this setting. This treatment can be administered in a manner that results in a low likelihood of late complications.


Subject(s)
Prostatectomy , Prostatic Neoplasms/radiotherapy , Adult , Aged , Aged, 80 and over , Follow-Up Studies , Humans , Male , Middle Aged , Neoplasm Recurrence, Local , Prostate-Specific Antigen/blood , Prostatic Neoplasms/surgery , Radiotherapy/adverse effects , Radiotherapy Dosage , Retrospective Studies , Salvage Therapy
15.
J Endourol ; 23(4): 579-82; discussion 582, 2009 Apr.
Article in English | MEDLINE | ID: mdl-19335142

ABSTRACT

Leiomyoma is the most frequent nonepithelial benign tumor of the bladder, and only about 170 cases have been reported in the literature. Most bladder wall leiomyomas are found incidentally and can be clinically followed if imaging and biopsy findings are consistent with the diagnosis. Resection is usually performed for symptomatic or enlarging masses and is indicated if the diagnosis is in question. We demonstrate imaging characteristics, port placement, operative technique, and surgical pathologic findings of the first reported case of robot-assisted laparoscopic resection of a bladder wall leiomyoma.


Subject(s)
Laparoscopy , Leiomyoma/surgery , Robotics/methods , Urinary Bladder Neoplasms/surgery , Aged , Humans , Leiomyoma/pathology , Magnetic Resonance Imaging , Male , Urinary Bladder Neoplasms/pathology
16.
Urology ; 69(2): 315-9, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17320671

ABSTRACT

OBJECTIVES: To determine whether urodynamic or clinical parameters can predict artificial urinary sphincter (AUS) outcome in patients who were incontinent after radical prostatectomy (RP). Incontinence after RP is secondary to intrinsic sphincter deficiency, but urodynamics have been advocated before AUS placement to detect factors that could limit surgical success. METHODS: We reviewed all AUSs placed for RP incontinence from January 1995 to December 2004. The preoperative clinical parameters and urodynamic parameters were correlated with surgical success using linear and logistic regression analysis, respectively. Surgical failure was defined as requiring more than one pad per day. RESULTS: The data from 86 patients (mean age 72 years) were analyzed. Of these 86 patients, 15 (17%) were wearing more than 1 pad per day at the last follow-up visit; 11 patients (13%) considered their operation a failure; and 20 patients (24%) had postoperative urgency. The presence of detrusor overactivity (P = 0.92), low first sensation (P = 0.52), low bladder compliance (P = 0.38), and bladder capacity less than 300 mL (P = 0.58) in patients did not predict for AUS failure compared with patients without these findings. No clinical parameters were found that demonstrated a statistical association with the number of pads per day. Older patients considered themselves less improved (P = 0.012) than did younger patients. CONCLUSIONS: No evidence has shown that patients who are incontinent after RP who have detrusor overactivity, a low first sensation, decreased compliance, or a low bladder capacity have worse post-AUS outcomes than other patients. Older patients tended to have decreased perceived improvement. We found no clinical or urodynamic parameter that would be a contraindication to AUS placement for post-RP incontinence.


Subject(s)
Prostatectomy/adverse effects , Prostatectomy/methods , Prostatic Neoplasms/surgery , Urinary Incontinence/surgery , Urinary Sphincter, Artificial , Urodynamics , Aged , Aged, 80 and over , Biopsy, Needle , Cohort Studies , Follow-Up Studies , Humans , Logistic Models , Male , Middle Aged , Neoplasm Staging , Postoperative Complications , Predictive Value of Tests , Preoperative Care , Probability , Prostate-Specific Antigen/blood , Prostatic Neoplasms/pathology , Retrospective Studies , Risk Assessment , Treatment Outcome , Urinary Incontinence/etiology , Urination/physiology
17.
J Urol ; 176(3): 985-90, 2006 Sep.
Article in English | MEDLINE | ID: mdl-16890677

ABSTRACT

PURPOSE: This study was performed to evaluate the results and prognostic factors associated with radiotherapy for a detectable serum prostate specific antigen level after radical prostatectomy. MATERIALS AND METHODS: From July 1987 through July 2003, 368 patients received radiotherapy for a detectable prostate specific antigen level (biochemical relapse) as the sole evidence of recurrence after radical prostatectomy for node negative prostate cancer. Estimated survival and relapse-free probabilities were obtained via Kaplan-Meier estimation. Associations of patient factors with survival and biochemical relapse were investigated using Cox proportional hazards models. RESULTS: With a median followup of 5 years the 5 and 8-year freedom from biochemical relapse were an estimated 46% (95% CI 41%-53%) and 35% (95% CI 29%-43%) while survival was 92% (95% CI 89%-95%) and 80% (95% CI 74%-87%), respectively. Patient and treatment variables showing evidence of association with biochemical relapse on multivariate analysis included pathological stage T3a or less vs T3b (seminal vesicle involvement, p = 0.029), pathological Gleason score 7 or less vs 8 or greater (p <0.001) and pre-radiotherapy prostate specific antigen (p <0.001). Four biochemical failure risk groups were created by assigning seminal vesicle involvement, Gleason score and pre-radiotherapy prostate specific antigen each a score of 0 to 2. These individual scores were summed. The freedom from biochemical failure at 5 years for each risk group was 0 to 1-69%, 2-53%, 3-26% and 4 to 5-6%. CONCLUSIONS: The presence of seminal vesicle involvement and high Gleason score in the radical prostatectomy specimen are inherent predictors of adverse outcome. Early referral for salvage radiotherapy can decrease subsequent biochemical relapse.


Subject(s)
Neoplasm Recurrence, Local/blood , Neoplasm Recurrence, Local/radiotherapy , Prostate-Specific Antigen/blood , Prostatectomy , Prostatic Neoplasms/blood , Prostatic Neoplasms/radiotherapy , Salvage Therapy , Adult , Aged , Aged, 80 and over , Follow-Up Studies , Humans , Male , Middle Aged , Prognosis , Prostatic Neoplasms/surgery
18.
Int J Radiat Oncol Biol Phys ; 65(5): 1585-92, 2006 Aug 01.
Article in English | MEDLINE | ID: mdl-16863936

ABSTRACT

PURPOSE: To compare the accuracy of imaging modalities, immobilization, localization, and positioning techniques in patients with prostate cancer. METHODS AND MATERIALS: Thirty-five patients with prostate cancer had gold marker seeds implanted transrectally and were treated with fractionated radiotherapy. Twenty of the 35 patients had limited immobilization; the remaining had a vacuum-based immobilization. Patient positioning consisted of alignment with lasers to skin marks, ultrasound or kilovoltage X-ray imaging, optical guidance using infrared reflectors, and megavoltage electronic portal imaging (EPI). The variance of each positioning technique was compared to the patient position determined from the pretreatment EPI. RESULTS: With limited immobilization, the average difference between the skin marks' laser position and EPI pretreatment position is 9.1 +/- 5.3 mm, the average difference between the skin marks' infrared position and EPI pretreatment position is 11.8 +/- 7.2 mm, the average difference between the ultrasound position and EPI pretreatment position is 7.0 +/- 4.6 mm, the average difference between kV imaging and EPI pretreatment position is 3.5 +/- 3.1 mm, and the average intrafraction movement during treatment is 3.4 +/- 2.7 mm. For the patients with the vacuum-style immobilization, the average difference between the skin marks' laser position and EPI pretreatment position is 10.7 +/- 4.6 mm, the average difference between kV imaging and EPI pretreatment position is 1.9 +/- 1.5 mm, and the average intrafraction movement during treatment is 2.1 +/- 1.5 mm. CONCLUSIONS: Compared with use of skin marks, ultrasound imaging for positioning provides an increased degree of agreement to EPI-based positioning, though not as favorable as kV imaging fiducial seeds. Intrafraction movement during treatment decreases with improved immobilization.


Subject(s)
Movement , Prostatic Neoplasms/radiotherapy , Gold , Humans , Immobilization/methods , Infrared Rays , Lasers , Male , Prostate/diagnostic imaging , Prostatic Neoplasms/diagnostic imaging , Prostheses and Implants , Radiography , Radiotherapy, Intensity-Modulated , Skin/anatomy & histology , Ultrasonography
19.
Urology ; 68(1): 132-6, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16777196

ABSTRACT

OBJECTIVES: To review 10-year outcomes of an alternative vesicourethral anastomotic technique performed after radical retropubic prostatectomy (RRP). METHODS: With institutional review board approval, 307 consecutive RRPs performed by one surgeon (mean patient age, 63.5 years; range, 35 to 77 years) from November 1994 to December 2004 with an alternative anastomosis were reviewed. Cox proportional hazard models with forward selection were used to investigate associations with outcomes and operative parameters. RESULTS: Mean estimated blood loss (EBL) was 550 mL. Sixty-three patients (20.5%) required blood transfusion. Mean anastomotic time ranged from 8 to 22 minutes (median, 11 minutes). Nine patients (2.9%) required surgical drain for more than 2 days. A total of 246 patients were available for at least 1-year continence follow-up (mean, 51 months). Of these, 160 patients (65.0%) never leaked or required a pad at point of last follow-up; 25 patients (10.2%) required 1 non-insurance pad or more per day. Only 3 patients (1.2%) have had incontinence interventions (one artificial sphincter and two collagen injections). Operative parameters statistically associated with wearing 1 pad per day or more were EBL (P = 0.035) and time to continence (P <0.001). Forty-three patients (17.5%) required stricture dilation, with a mean time to intervention of 6 months (range, 1 to 33 months). No patient required incision of bladder neck contracture. The only statistically associated factors with stricture formation were increased age and increased EBL. CONCLUSIONS: The alternative anastomotic technique is efficient and provides proper urethral alignment with a minimal rate of prolonged urinary extravasation. Long-term urinary continence is excellent, and stricture rates are acceptable compared with other anastomotic techniques.


Subject(s)
Prostatectomy , Prostatic Neoplasms/surgery , Urethra/surgery , Urinary Bladder/surgery , Adult , Aged , Anastomosis, Surgical , Humans , Male , Middle Aged , Prostatic Neoplasms/pathology , Urethral Stricture/etiology , Urinary Incontinence/etiology , Urologic Surgical Procedures/adverse effects , Urologic Surgical Procedures/methods
20.
Urology ; 67(3): 622.e9-11, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16504263

ABSTRACT

Thirteen reported cases of renal pelvic sarcomatoid carcinoma have been documented since 1961, and all patients presented with metastatic disease or advanced renal parenchyma involvement. The mean survival was shorter than 9 months, and adjuvant therapy appeared to offer no benefit. We present the case of a 61-year-old man with gross hematuria and a large filling defect on computed tomography excretory urography. Surgical pathologic examination after laparoscopic nephroureterectomy was consistent with renal pelvis-confined sarcomatoid carcinoma of transitional cell origin. Adjuvant therapy was not given secondary to the organ-confined nature of disease. The patient was without recurrence for more than 1 year.


Subject(s)
Carcinosarcoma/pathology , Kidney Neoplasms/pathology , Kidney Pelvis , Carcinoma, Transitional Cell/pathology , Carcinosarcoma/surgery , Humans , Kidney Neoplasms/surgery , Male , Middle Aged
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