The effects of age and sex on hand movement structure.

The aim was to investigate the effects of age and sex on hand function and ascertain age-related changes (magnitude and rate) by assessing a broad range of functional tasks with the dominant and non-dominant hands. A representative sample of 635 adults (114 males and 491 females) aged 50 years and over completed motor performance series of the Vienna Test System Parametric and non-parametric analysis and simple linear regression was used to examine the relationships. Significant relationships were observed between task performance and age and sex, although the contributions of both factors differed by varying degree. Compared with males, the females performed significantly better than males in the majority of tests, particularly with the dominant hand, although greater age-related reductions were observed in performance. Among the skills quantifying hand function, age accounted for the most variance in hand and finger dexterity.

The optimal value of BMI for the lowest risk of osteoporosis in postmenopausal women aged 40-88 years.

The aim of this paper is to establish the optimal values of the body mass index (BMI) which would indicate the most favourable preservation of the bone mineral density in postmenopausal women. The material consists of the data of 369 healthy women aged between 40 and 88 years (mean age 67.84, SD=6.70) inhabitants of Wroclaw, which were followed up between 2001 and 2006. The absolute measure of bone mineral density (BMD) of the femoral neck was assessed using dual energy X-ray absorptiometry (DEXA), expressed in g/(100mm(2)) and was transformed to T-score values. According to the value of BMI, the women were divided into eight groups, the reference group with value between 18.0 and 21.9kg/m(2) and seven other groups beginning with the value 22.0 with a 2-point interval. Postmenopausal status was defined according to the occurrence of menstruation within the last 360 days. The women with osteopenia and osteoporosis were pooled together and comprised the risk group, whereas the other women comprised the normal group (T-score values above -1.0). The adjusted odds ratio showed the highest value for intervals between 24.0 and 25.9 units of BMI, and the lowest value for interval 26.0-27.9 units of BMI. The Youden index showed the lowest value in the 26.0-27.9BMI kg/m(2) interval. For our sample the optimal value of BMI, with the lowest risk of osteopenia and/or osteoporosis was the value of 26.9kg/m(2). A further increase of BMI does not result in a favourable effect on the bones, it rather intensifies negative phenomena in the body resulting in the onset of many diseases.

Lead and growth status of school children living in the copper basin of south-western Poland: differential effects on bone growth.

OBJECTIVE: The study analyzed the relationship between blood lead (BPb) levels and growth status of upper and lower body segments among schoolchildren living in the copper basin of south-western Poland. MATERIALS AND METHODS: Schoolchildren 7-15 years of age (463 males, 436 females) living in the vicinity of copper smelters and refineries were tested for blood lead. Weight, height, symphyseal height (leg, lower segment length), and arm length were measured. Trunk (upper segment including head and neck) length was estimated as height minus symphyseal height. The BMI was calculated using weight/height2 (kg m-2). RESULTS: Mean blood lead in the total sample was 7.7 +/- 3.5 micro g dL-1 (2.0-33.9 micro g dL-1). Blood lead level was significantly and linearly related to reduced weight, height, trunk, leg, and arm lengths. The estimated reduction in height was 5 mm per 1 micro g dL-1 increase in blood lead (5.0 cm per 10 micro g dL-1). The reduction occurred in leg length (males, 64%; females 72%) compared to trunk length (males, 36%; females, 28%). Estimated reductions in arm length were 2.0 cm (males) and 2.5 cm (females) per 10 micro g dL-1 increase in blood lead. Hence, limb (leg and arm) lengths were markedly reduced. CONCLUSIONS: Linear skeletal growth was reduced with increased blood lead, even at levels below that considered for action by US CDC standards. The reduction in height occurred primarily in leg length. Arm length was also reduced, suggesting limb lengths in general were affected by blood lead. Results are consistent with lead-associated interruption of (1) major epiphyseal growth plate chondrocyte hyperplasia, hypertrophy, and interrupted matrix calcification as a primary cause of stunted long bone growth, and reduced stature; and (2) attenuated osteoblast activity (proliferation and migration) as a secondary cause of stunted growth in the study population.

Estimation of health state and physical efficiency of children from rural area of Lubin-Glogow copper-basin and lead levels in blood serum. Preliminary results.

The aim of the work was to estimate the health state and physical efficiency of children from rural area of Lubin-Glogów Copper-Basin in correlation with lead levels in blood. Lead concentration in blood showed increase tendency together with age of the children. In both sexes together with rise in lead concentration in blood enlargement of palatine tonsils was observed. In children with a higher lead concentration in blood lower values of physical fitness parameters are recorded.