Anticoagulation management around percutaneous bedside procedures: is adjustment required?

BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) and percutaneous dilatational tracheostomy (PDT) are frequently performed bedside in the intensive care unit. Critically ill patients frequently require anticoagulant (AC) and antiplatelet (AP) therapies for myriad indications. There are no societal guidelines proffering strategies to manage AC/AP therapies periprocedurally for bedside PEG or PDT. The aim of this study is to evaluate the management of AC/AP therapies around PEG/PDT, assess periprocedural bleeding complications, and identify risk factors associated with bleeding. METHODS: A retrospective, observational study of all adult patients admitted from October 2004 to December 2009 receiving a bedside PEG or PDT was conducted. Patients were identified by procedure codes via an in-hospital database. A medical record review was performed for each included patient. RESULTS: Four hundred fifteen patients were included, with 187 PEGs and 352 PDTs being performed. Prophylactic anticoagulation was held for approximately one dose before and two doses or less after the procedure. There was wide variation in patterns of holding therapy in patients receiving anticoagulation via continuous infusion. There were 19 recorded minor bleeding events, 1 (0.5%) with PEG and 18 (5.1%) with PDT, with no hemorrhagic events. No association was found between international normalized ratio, prothrombin time, or activated partial thromboplastin time values and bleed risk (p = 0.853, 0.689, and 0.440, respectively). Platelet count was significantly lower in patients with a bleeding event (p = 0.006). CONCLUSIONS: We found that while practice patterns were quite consistent in regard to the management of prophylactic anticoagulation, it varied widely in patients receiving therapeutic anticoagulation. It seems that prophylactic anticoagulation use did not affect bleed risk with PEG/PDT.

Effects of differences in percent total body surface area estimation on fluid resuscitation of transferred burn patients.

We sought to analyze the effect that differences in estimation of burn size and burn resuscitation had on complications and death among our transferred burn patients, in comparison with outcomes for burn patients directly admitted to our rural Level 1 trauma center. A retrospective chart review was performed for all patients suffering thermal injuries who were treated at a rural Level I trauma center and regional burn center. Percent TBSA burn estimates at referring hospitals were compared to burn center estimates. The Parkland formula was used to calculate the difference between the theoretical and actual resuscitation volumes given prior to admission. Of 127 burn patients, 82 (65%) were transferred from outside hospitals. For small burns (<20% TBSA), the mean estimate difference between outside hospitals and the burn center was 4.3 +/- 6.9%. For large burns (> or =20% TBSA), the mean estimate difference was -4.9 +/- 9.1% (P < .0002). The mean difference in intravenous fluid administered prior to admission to the burn center and the Parkland formula guideline was an excess of 554 +/- 1099 ml for small burns and a deficit of -414 +/- 2081 ml for larger burns (P = .03, Wilcoxon's rank-sum test). Differences in burn estimation and deviation from the Parkland formula were not statistically significant for complication and death. In the rural, transferred burn patient, smaller burns tended to be overestimated and overresuscitated and larger burns tended to be underestimated and underresuscitated.

A needs assessment for regionalization of trauma care in a rural state.

Systems of trauma care in urban areas have a demonstrated survival benefit. Little is known of the benefit of trauma system organization in rural areas. We hypothesized that examination of all trauma deaths during a 1-year period would provide opportunities to improve care in our rural state. We used a medical examiner database of trauma deaths occurring during a 1-year period. Five board-certified surgeons analyzed deaths as preventable (P), potentially preventable (PP), and non-preventable (NP) using modified Delphi technique. There were 223 trauma deaths during a 1-year period. Most (63%) died at the scene prior to any medical intervention. Adjudication of the deaths demonstrated 5 P (2%; 95% CI 1-5%), 36 PP (16%; 95% CI 12-27%), and 179 NP (81%; 95% CI 76-86%). Agreement among trauma surgeons was only moderate with a k of 0.46. Suicide accounted for a significant number of the overall trauma deaths at 32 per cent. Rural trauma system design should focus on discovery, as that is where the majority of deaths occur. Suicide is a significant problem in this rural state that should be aggressively targeted with prevention programs.

Workload redistribution: a new approach to the 80-hour workweek.

BACKGROUND: The new Accreditation Council for Graduate Medical Education-mandated 80-hour resident work week has resulted in busy trauma services struggling to meet these strict guidelines, or face loss of accreditation. METHODS: Beginning in July 2003, our Level I trauma service began a policy of direct admission of isolated neurosurgical or orthopedic injuries to the specific subspecialty service after complete evaluation by the trauma service in the emergency department for associated injuries. Complications, missed injuries, delayed diagnoses, and admission rates were compared in two 6-month periods: PRE, before the policy change; and POST, after the new policy had been instituted. Resident work hours were likewise compared over the two time periods. RESULTS: Selected single-system injury admission to subspecialty services resulted in a 15% reduction in admissions to the trauma service. There were no significant differences in the overall complication rate, delayed diagnoses, or missed diagnoses between the PRE and POST time periods. Overall, there was a 9.7% reduction in resident work hours (p = 0.45; analysis of variance) between the PRE and POST periods, which allowed them, on average, to meet the Accreditation Council for Graduate Medical Education 80-hour workweek mandate. CONCLUSION: Direct admission of patients with isolated injuries to subspecialty services is safe and decreases the workload of residents on busy trauma services.