Risperidone for aggression and self-injurious behavior in adults with mental retardation.

Risperidone has proven efficacy with reduced likelihood of causing extrapyramidal symptoms in the treatment of schizophrenia. Initial work suggests its utility in the management of aggression and self injury in patients with mental retardation. The use of risperidone in eight adult patients with moderate to profound mental retardation is described. Risperidone in these individuals was associated with significant reduction in aggression and self injurious behavior. Side effects were primarily those of sedation and restlessness. These cases illustrate the possible utility of risperidone in the treatment of aggression and self injury in adult patients with moderate to profound mental retardation.

Peer versus adult models and autistic children's learning: acquisition, generalization, and maintenance.

This study compared the effectiveness of a peer model and an adult model in teaching an expressive language task to four autistic boys. A BCBC design, counterbalanced across subjects, was used. After training criterion was reached, generalization of responding to an extratherapy school setting and to the home was measured. Thirteen weekly maintenance probes were conducted after training in each condition. Results indicated that all children learned through observing the peer and adult models and that few consistent differences occurred across the two conditions. The degree of generalization and maintenance of responding was consistently high in both conditions. The relation of these data to the modeling literature on autistic children and implications for developing educational programs for autistic children are discussed.