Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters









Database
Language
Publication year range
1.
Inversion of enantioselectivity of asymmetric biocatalytic decarboxylation by site-directed mutagenesis based on the reaction mechanism.
Ijima, Yoichiro; Matoishi, Kaori; Terao, Yosuke; Doi, Nobuhide; Yanagawa, Hiroshi; Ohta, Hiromichi.
Chem Commun (Camb) ; (7): 877-9, 2005 Feb 21.
Article in English | MEDLINE | ID: mdl-15700067

ABSTRACT

The introduction of two mutations (G74C/C188S) based on the estimated reaction mechanism resulted in the inversion of enantioselectivity of arylmalonate decarboxylase, which catalyses the asymmetric decarboxylation of arylmethylmalonate to give optically active arylpropionate.


Subject(s)
Carboxy-Lyases/chemistry , Carboxy-Lyases/genetics , Methylmalonic Acid/chemistry , Propionates/chemical synthesis , Amino Acid Sequence , Catalysis , Decarboxylation , Molecular Conformation , Molecular Sequence Data , Mutagenesis, Site-Directed , Stereoisomerism
SEND TO:
Email
Export
Print
RSS
XML
SELECTION OF CITATIONS
SEARCH DETAIL