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BMC Infect Dis ; 18(1): 381, 2018 08 07.
Article in English | MEDLINE | ID: mdl-30086720

ABSTRACT

BACKGROUND: Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has been linked to epidemic myalgia, regardless of the presence of underlying diseases, immunosuppression, or sex. CASE PRESENTATION: We describe an adult case of severe systemic myalgia and orchiodynia after infection with HPeV-3, which was transmitted from the child of the patient. Interleukin-6 (IL-6) level was found to be elevated in the patient's serum. CONCLUSION: Severe myalgia associated with HPeV-3 infection is potentially caused by an elevated serum level of IL-6.


Subject(s)
Interleukin-6/blood , Parechovirus/isolation & purification , Picornaviridae Infections/diagnosis , Pleurodynia, Epidemic/diagnosis , Pleurodynia, Epidemic/virology , Adult , Child, Preschool , Diarrhea/blood , Diarrhea/complications , Diarrhea/virology , Humans , Male , Nuclear Family , Parechovirus/genetics , Parechovirus/immunology , Picornaviridae Infections/blood , Picornaviridae Infections/epidemiology , Pleurodynia, Epidemic/blood , Sepsis/blood , Sepsis/diagnosis , Sepsis/epidemiology , Sepsis/virology
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