ABSTRACT
While parenchymal metastases are common in solid systemic cancers, subependymal metastases are rare. Approximately half of the reported cases of intraventricular metastases originate from renal carcinoma. A 65-year-old man presented with general fatigue, appetite loss, nausea, and disorientation. Radiological examination revealed diffuse periventricular tumors. The patient underwent an open biopsy via right frontotemporal craniotomy. The patient was diagnosed with metastatic small cell lung carcinoma after histopathological examination. Although subependymal metastases from solid systemic cancer are very rare, this ventricular wall abnormality in the cancer patients must not be overlooked. Many small subependymal metastases might be missed on routine examination.
Subject(s)
Brain Neoplasms/secondary , Lung Neoplasms/diagnostic imaging , Small Cell Lung Carcinoma/diagnostic imaging , Small Cell Lung Carcinoma/secondary , Aged , Biopsy/methods , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/surgery , Fatal Outcome , Humans , Lung Neoplasms/pathology , Male , Small Cell Lung Carcinoma/surgery , Tomography, X-Ray Computed/methodsABSTRACT
Prader-Willi Syndrome (PWS) is a rare genetic disorder characterized by physical, psychological and physiological abnormalities. Obesity and related cardiovascular diseases are a common problem in adult patients with PWS. This report describes a case of adult PWS with heart failure associated with marked obesity and sleep-disordered breathing that was successfully treated with oxygen therapy, adaptive servoventilation, medications, diet therapy and rehabilitation.
