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Pediatr Infect Dis J ; 30(9): 813-5, 2011 Sep.
Article in English | MEDLINE | ID: mdl-21494173

ABSTRACT

Disseminated congenital toxoplasmosis mimicking septic shock is unusual. We report a fatal case of disseminated congenital toxoplasmosis that was acquired after a third trimester maternal primary infection. The child had severe pneumonitis, purpura, and hepatitis. After 5 days of treatment, quantitative polymerase chain reaction analysis showed that parasite loads in the serum and in tracheal aspirates had decreased. The child died of refractory hypoxemia. Genotyping revealed a type II strain.


Subject(s)
Toxoplasma/classification , Toxoplasmosis, Congenital/parasitology , Adult , Anti-Infective Agents/therapeutic use , Antibodies, Protozoan/immunology , DNA, Protozoan/genetics , Fatal Outcome , Female , Genotype , Humans , Infant, Newborn , Male , Pregnancy , Pregnancy Complications, Parasitic/immunology , Pregnancy Complications, Parasitic/parasitology , Toxoplasma/immunology , Toxoplasma/isolation & purification , Toxoplasmosis, Congenital/diagnosis , Toxoplasmosis, Congenital/drug therapy
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