[Morphofunctional evaluation of the results of reconstructive operations of gastroenteroanastomosis in peptic ulcer]. / Morfofunktsional'naia otsenka rezul'tatov rekonstruktivnykh operatsii pri pepticheskoi iazve gastroenteroanastomoza.

The mucosa of the gastric stump, abducting and adducting loops of small intestine in patients with peptic ulcers of gastrointestinal anastomosis has been examined with scanning, transmission electron and light microscopy, morphometry, and the study of secretion at various periods after reconstructive surgery combined with vagotomy. An increase of the number of chief and parietal cells in the gastric stump fundal glands, increase of the thickness of the mucosa due to the deepening of the crypts of the adducting and abducting loops of the small intestine, and alteration of the mucosal microrelief of the gastric stump and small intestine are noted in peptic ulcers of gastrointestinal anastomosis especially near the site of anastomosis. This is accompanied by an increase of mucosal secretory activity. Reconstructive operations combined with vagotomy cause a reduction in chief and parietal cells number, smoothing of the mucosal microrelief and decrease of gastric secretory activity.

[Changes in the gastric mucosa in complicated forms of peptic ulcer and postgastrectomy syndromes]. / Izmeneniia slizistoi obolochki zheludka pri oslozhnennykh formakh iazvennoi bolezni i postgastrorezektsionnykh sindromakh.

Complex studies of the secretory function of the stomach have shown its activity to depend upon the type of gastric ulceration. It allows gastric ulcers to be differentiated into those with hyposecretory (primary ulcers) and hypersecretory (associated and secondary ulcers) syndromes. High secretory activity of the stomach with duodenal ulcers is confirmed by the results of morphological investigations.

[Morphofunctional state of the gastric mucosa in primary, combined and secondary stomach ulcer]. / Morfofunktsional'noe sostoianie slizistoi obolochki zheludka pri pervichnykh, sochetannykh i vtorichnykh zheludochnykh iazvakh.

The morphofunctional condition of the gastric mucosa was studied in primary, combined, and secondary peptic ulcers. The secretory function of the stomach in primary ulcers was found not to differ from that in normal subjects. An increase in the number of all kinds of epithelial cells of fossi and glands of the fundal part was observed, the percentage ratio of the cells not changing significantly. In secondary peptic ulcers arising in the presence of long-existing stenosing duodenal ulcers, that is due to gastrostasis, the secretory function was markedly increased. In this condition there was a significant increase in the number of principal and parietal cells. Their ultrastructure indicated a high functional activity. No principal differences in the condition of the secretory function of the stomach in patients with combined and secondary ulcers were found.